A gallbladder and cancerous cells

Gallbladder cancer

Gallbladder cancer is a highly lethal disease and is the most common cancer of the biliary tract. 


  • Cover image NRDP

    Topics soon to be featured in the journal include Pre-eclampsia, Fetal alcohol spectrum disorders and Monogenic diabetes.

  • A new Comment article discusses the need for diversity in clinical trial populations to minimize outcome disparities.

    Homogeneous clinical trial populations do not accurately represent the patient populations served. Diversity in research participation is needed to minimize outcome disparities and achieve social equity.

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    Finding it hard to navigate the flood of scientific literature? Take a look at this animation to learn how Nature Reviews can help you stay up-to-date in your field by filtering and highlighting the most impactful research, or visit www.springernature.com/naturereviews


  • Medication overuse headache is a secondary headache disorder that occurs in those with a primary headache disorder (commonly tension-type headache or migraine). This Primer reviews the epidemiology, pathophysiology, diagnosis and treatment of medication overuse headache, and discusses how this disorder affects the quality of life of patients.

    • Sait Ashina
    • Gisela M. Terwindt
    • Richard B. Lipton
  • The ichthyoses are a group of dermatological disorders characterized by generalized scaly, erythematous skin, accompanied by epidermal barrier function disruptions. This Primer by Gutiérrez-Cerrajero and colleagues summarizes the epidemiology, mechanisms, diagnosis and treatment of ichthyosis, and discusses patient quality of life and open research questions for this condition.

    • Carlos Gutiérrez-Cerrajero
    • Eli Sprecher
    • Rogelio González-Sarmiento
  • Hazardous drinking and alcohol use disorder are associated with substantial harms to both the individual and others. This Primer discusses the epidemiology, mechanisms, diagnosis and management of these disorders, and also summarizes screening, prevention and the quality of life issues faced by individuals with these disorders.

    • James MacKillop
    • Roberta Agabio
    • Jürgen Rehm
  • Burkitt lymphoma is an aggressive form of B cell lymphoma that can affect children and adults. Its research has been central in advancing haematopathology and cancer research. This Primer by Siebert and colleagues summarizes the epidemiology, mechanisms, diagnosis and treatment of this disorder, patient quality of life and open research questions.

    • Cristina López
    • Birgit Burkhardt
    • Reiner Siebert
  • Osteosarcoma is the most common primary malignant tumour of the bone. This Primer by Gorlick and colleagues summarizes the epidemiology, mechanisms, diagnosis and treatment of this disorder as well as the quality of life of patients and open research questions.

    • Hannah C. Beird
    • Stefan S. Bielack
    • Richard Gorlick
  • Myelodysplastic syndromes (MDS) are a group of blood cancers involving dysregulated haematopoiesis, which may progress to acute myeloid leukaemia. This Primer provides an overview of the epidemiology, diagnosis, pathogenesis and management of MDS.

    • Huan Li
    • Fang Hu
    • Yang Liang
  • Current medical education propagates bias and power imbalances in medical institutions, which cascade into professional practices and organizations. To serve the needs of all, we need an understanding of how modern medicine was set up, the biases that are embedded in the structures of health care and strategies to transform those structures.

    • Amali U. Lokugamage
    • Rupa Marya
  • Sexual and gender minorities (SGM) experience negative attitudes, stigma, denial of care or low-quality care from health-care providers. Increased awareness and adequate training of health-care professionals and students are required to reduce biases and barriers to care for SGM people.

    • Monica Malta
  • Specific chromosomal abnormalities are associated with development of multiple myeloma and its precursor syndromes. This poster explores the process of plasma cell development, and the types and frequencies of chromosomal abnormalities and other genetic alterations that are involved in development and progression of multiple myeloma.

    • Aneta Mikulasova
    • Gareth J. Morgan
    • Brian A. Walker
  • Planetary and human health are inseparably connected; yet, health-care systems produce considerable amounts of greenhouse gas emissions, waste and pollution. A growing movement to measure and mitigate the health sector’s own climate damage is underway, supported by national policies and clinical innovation.

    • Frances Mortimer
    • David Pencheon
A group of women with diverse backgrounds and physiques are standing together, supporting each other and looking ahead.

Women’s health

Research into women’s health has suffered from historical neglect and lack of funding.


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