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Series |
Insights into the molecular mechanisms of tumor angiogenesis have led to the identification of potential angiogenic targets and the development of novel antivascular agents. Many of these agents have shown promising antitumor activity. This series of articles examines the advances in our understanding of this complex process and covers topics such as vessel branching morphogenesis, small-molecule and large-molecule therapies, management of adverse effects caused by the antiangiogenic agents and biomarkers of response and resistance.