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  • In this Journal Club, Taboada and Riechelmann discuss the importance of a study outlining a novel neuroendocrine neoplasm classification system.

    • Rodrigo Gomes Taboada
    • Rachel P. Riechelmann
    Journal Club
  • In this Journal Club, Hajj discusses a study demonstrating that oncogene activation modulates immune control through both transcription and translation.

    • Glaucia N. M. Hajj
    Journal Club
  • In this Journal Club, Kinker & Medina discuss a study showing the role of tumour-associated tertiary lymphoid structures in improving immunotherapy response and overall survival in patients with melanoma.

    • Gabriela Sarti Kinker
    • Tiago da Silva Medina
    Journal Club
  • In this Journal Club, Felismino and Coimbra discuss the impact of TCGA’s comprehensive molecular characterization of gastric adenocarcinoma.

    • Tiago Cordeiro Felismino
    • Felipe José Fernández Coimbra
    Journal Club
  • In this Journal Club, Kanaan and Copeland discuss a study showing that a high 1,25(OH)2D:25(OH)D molar ratio, indicative of vitamin D metabolism, is inversely related to the risk of highly aggressive prostate cancer in African American men.

    • Yasmine Kanaan
    • Robert L. Copeland
    Journal Club
  • In this Journal Club, Abbas and Kurian discuss a study showing that using iron selenide quantum dots as biometric probes is superior to conventional organic fluorophores — with higher biocompatibility and quantum yield — in detecting tumour cell growth both in vitro and in vivo.

    • Muneer Abbas
    • Philip Kurian
    Journal Club
  • In this Journal Club, H. Mir and S. Singh discuss a study that established the significance of signalling via the G-protein-coupled receptors CXCR1 and CXCR2 in the extrusion of neutrophil extracellular traps, which can be targeted for cancer therapy.

    • Hina Mir
    • Shailesh Singh
    Journal Club
  • In this Journal Club, S. K. Singh and R. Singh discuss a study that used bioreactive, tumour microenvironment-modulating nanoparticles with doxorubicin to treat breast tumour xenograft-bearing mice, leading to reversal of immunosuppression and tumour shrinkage.

    • Santosh Kumar Singh
    • Rajesh Singh
    Journal Club
  • Xie and Gu discuss a study that reported the development of a CAR T therapy-based multi-antigen targeting strategy for the treatment of glioblastoma (GBM) in mice, overcoming antigen specificity and heterogeneity.

    • Guiqin Xie
    • Xinbin Gu
    Journal Club
  • In this Journal Club, Desiree Rivers discusses a study that developed and assessed the impact of SurvivorSHINE, a web-based lifestyle intervention for cancer survivors.

    • Desiree Rivers
    Journal Club
  • In this Journal Club, Ashktorab and Brim discuss a study that established consensus molecular subtypes for colorectal cancer (CRC) with potential for direct clinical translation and better classification of CRC.

    • Hassan Ashktorab
    • Hassan Brim
    Journal Club
  • In this Journal Club, Robert L. Copeland and Yasmine Kanaan discuss a paper that reports how ERβ and IGF2 signalling may contribute to the heterogeneity of triple-negative breast cancer observed in patients with different ancestries in the USA.

    • Robert L. Copeland
    • Yasmine Kanaan
    Journal Club
  • In this Journal Club, Brian Rivers highlights a study aimed at enhancing the participation of African American patients in cancer clinical trials.

    • Brian M. Rivers
    Journal Club
  • In this Journal Club, Hassan Brim and Hassan Ashktorab discuss a publication that reported the involvement of the microbiome in colorectal cancer metastasis.

    • Hassan Brim
    • Hassan Ashktorab
    Journal Club