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Selected, recent articles from across the Nature Portfolio that document the recent progress in understanding the biology of EV-mediated cell–cell communication and advances in clinical translation of EVs.
One of the fundamental biological processes in life is the cell cycle leading from DNA replication to cell division. While it has been studied for decades and our knowledge has matured, sophisticated experimental approaches have rejuvenated the field. In addition, cell cycle regulators have emerged as cancer therapy targets. This collection showcases ground-breaking cell cycle papers and reviews, ranging from basic discoveries to clinical applications.
Survival for patients with many types of malignant primary brain tumours or with brain metastasis has not improved much in the past 10 years, despite the introduction of some new treatments and despite our improved understanding of the biological bases of brain tumour development and metastasis.
Metastasis, the dissemination of tumour cells from a primary site leading to their colonization at a distant organ, is ultimately what kills most patients with cancer. This Collection from Nature Reviews Cancer presents our most recently published articles on the topic highlighting the advances made in our understanding of the metastatic process.
This series of articles explores how changes in diet and systemic metabolism can influence tumour development and progression, how this is affected by the presence of metabolic disease and how we can use this knowledge to improve anticancer therapy.
In this Collection, Nature Reviews Clinical Oncology and Nature Reviews Cancer together present a selection of our most recent articles covering the biology and treatment of haematological cancers highlighting the remarkable advances that have been made in both basic and translational research.
This Collection from Nature Reviews Cancer brings together some of our most recently published articles focused on understanding the role the tumour microenvironment plays in tumour progression as well as therapeutic responses and resistance.
Stem cells are well on their way into the clinic and can be used in a variety of applications, such as disease modelling, drug screening and for regenerative medicine. This collection showcases research articles, reviews and protocols from across the Nature journals to highlight the striking advances made in basic and translational stem cell research.