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  • Based on a virtual discussion during the American Association for Cancer Research (AACR) 2020 Annual Meeting, we asked several scientists actively working to improve representation of Black American populations in cancer research how they are addressing these issues.

    • John D. Carpten
    • Lola Fashoyin-Aje
    • Robert Winn
  • In this Viewpoint article, we asked four experts to provide their opinions on important aspects of brain metastasis biology, focusing on the unique microenvironment and therapeutic targets in the brain, preclinical models and how studying brain metastases could inform primary brain tumour biology.

    • Adrienne Boire
    • Priscilla K. Brastianos
    • Manuel Valiente
  • In this Viewpoint article, we asked four female scientists to describe their experiences of gender representation during their scientific careers and to identify the challenges and possible solutions to empowering women in cancer research and science more generally.

    • Christina A. Mitchell
    • Martine F. Roussel
    • Ashani T. Weeraratna
  • In this Viewpoint, we have asked recipients of the Nature Awards for Mentoring in Science about their views on good mentoring, and how mentorship can help to achieve a positive research culture and contribute to scientific discovery in cancer research.

    • Martin Clynes
    • Anita Corbett
    • Julie Overbaugh
  • In this Viewpoint article, we asked four scientists working on the cancer microbiome to provide their opinions on the current state of the field, where the research is heading and the challenges of implementing this field for clinical utility.

    • Eran Elinav
    • Wendy S. Garrett
    • Jennifer Wargo
  • In this Viewpoint article, we asked four scientists working in the field of epithelial to mesenchymal transition (EMT) to provide their opinions on the role of this complicated phenomenon in cancer biology as well as the challenges of this fast-moving field and the directions it should take in the future.

    • Thomas Brabletz
    • Raghu Kalluri
    • Robert A. Weinberg
  • In this Viewpoint article, we asked four scientists working to target important, but so-called 'undruggable', proteins in cancer for their opinions on the most crucial advances, as well as the challenges and what the future holds for this important area of cancer research.

    • Chi V. Dang
    • E. Premkumar Reddy
    • Laura Soucek
  • Many patients have now received various types of immunotherapy, so we asked three scientists to give their views on whether acquired resistance to immunotherapy exists in patients and the future challenges posed by immunotherapy.

    • Nicholas P. Restifo
    • Mark J. Smyth
    • Alexandra Snyder
  • Cancer incidence varies in different racial and ethnic groups, and this can be partly attributed to differences in biological factors. However, identifying these factors and exploiting them to help eliminate cancer disparities has proved challenging. This Viewpoint highlights the crucial advances and challenges, as well as what the future holds, for this area of research.

    • Brian E. Henderson
    • Norman H. Lee
    • Hongbing Shen
  • Four leading tumour immunologists provide their opinions on the determinants of immunogenicity and how we might therapeutically improve tumour immunogenicity in the future.

    • Thomas Blankenstein
    • Pierre G. Coulie
    • Elizabeth M. Jaffee
  • Opinions on where we should progress next with cancer research are diverse. In this article, four top cancer researchers from across the globe discuss their thoughts on the current state of cancer research and what progress might be expected in the next 10 years.

    • Ya Cao
    • Ronald A. DePinho
    • Karen Vousden