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This protocol describes NetworkAnalyst, a web-based tool for performing network analysis and visualization from gene lists and meta-analysis of gene expression datasets, and for displaying results as protein-protein interaction networks, heatmaps and chord diagrams.
Phyre2 is a web-based tool for predicting and analyzing protein structure and function. Phyre2 uses advanced remote homology detection methods to build 3D models, predict ligand binding sites, and analyze amino acid variants in a protein sequence.
To be useful for biological assays, quantum dots need to be made soluble and stable in biologically relevant matrices. In this protocol, a ligand containing a lipoic acid–zwitterion moiety capable of photoligation to the quantum dot is used.
This protocol is for generating microfluidic prototypes useful for biochemical assays using a print (printer toner on transparency sheets), cut (with a CO2 laser cutter) and laminate (with a standard office laminator) approach.
Skyline is a targeted proteomics environment that can be used in the detection and quantitation of peptides. In this protocol the MS/MS peptide data is generated by data-independent acquisition on a Q-Exactive mass spectrometer.
This is a protocol for studying several parameters of migration, including total and effective migration, velocity and cell polarization, in unharmed cells.
Nanocatalysts made up of Co3O4 surrounded by nitrogen-doped graphene layers are excellent activators of H2 and O2 for the hydrogenation and oxidation of organic compounds. They are environmentally benign, as water is the only reaction by-product.
Performing biochemical reactions within liposomes requires the supply of reagents and removal of products present in very small quantities. By using this protocol, a liposome dialyzer can be easily constructed to enable reagent exchange in small volumes.