Hot Topics in 2019

Biological fingerprints for psychosis

• Carol A. Tamminga
• Brett A. Clementz

The upside of stress: a mechanism for the positive motivational role of corticotropin releasing factor

• Julia C. Lemos
• Veronica A. Alvarez

The complexity of pharmacology of cannabidiol (CBD) and its implications in the treatment of brain disorders

• Sonja Elsaid
• Bernard Le Foll

Is depression a disorder of electrical brain networks?

• Yael Grossman
• Kafui Dzirasa

Selection criteria for neurophysiologic biomarkers to accelerate the pace of CNS therapeutic development

• Gregory A. Light
• Neal R. Swerdlow

TRPV1 and MOR working in tandem: implications for pain and opioids use

• Nasser Abdullah
• Christophe Altier

Sleep and EEG biomarkers as avenues toward new treatment approaches in Angelman syndrome

• Christopher J. McDougle
• Christopher J. Keary

Role for kappa-opioid system in stress-induced cocaine use uncovered with PET

• Derek Blevins
• Diana Martinez

Towards objective definition of psychopathology in post-traumatic stress disorder

• Amit Etkin

Linking actions with their consequences within the ventrolateral orbital cortex

• Dan C. Li
• Shannon L. Gourley

Contributions of nonneuronal brain cells in substance use disorders

• Kathryn J. Reissner
• Mikhail V. Pletnikov

Targeting neuroinflammation with brain penetrant P2X7 antagonists as novel therapeutics for neuropsychiatric disorders

• Anindya Bhattacharya
• Marc Ceusters

Physiological roles for neuromodulation via G_i/o GPCRs working through Gβγ–SNARE interaction

• Heidi E. Hamm
• Simon T. Alford

Intra-individual changes in methylome profiles: an epigenetic ‘scar’ of early-life adversity?

• Ali Mortazavi
• Tallie Z. Baram

The striatum specifies the statistics of behavior

• Jeffrey E. Markowitz
• Sandeep Robert Datta

Dopamine release drives motivation, independently from dopamine cell firing

• Ali Mohebi
• Joshua D. Berke

MDMA-assisted psychotherapy for posttraumatic stress disorder: A promising novel approach to treatment

• Eric Vermetten
• Rachel Yehuda

Regulation of fear extinction and relapse by hippocampal engrams

• Michael R. Drew
• Emma T. Brockway

Spatial transcriptomics: putting genome-wide expression on the map

• K. R. Maynard
• A. E. Jaffe
• K. Martinowich

MDMA enhances pleasantness of affective touch

• Harriet de Wit
• Anya K. Bershad