npj Systems Biology and Applications

npj Systems Biology and Applications

Alzheimer’s disease rewires gene coexpression networks coupling different brain regions

Sanga Mitra
Kailash BP
Manikandan Narayanan

Article 09 May 2024

Featured

Positive-unlabeled learning identifies vaccine candidate antigens in the malaria parasite Plasmodium falciparum

Renee Ti Chou
Amed Ouattara
Michael P. Cummings
ArticleOpen Access27 Apr 2024
Making drugs from T cells: The quantitative pharmacology of engineered T cell therapeutics

Daniel C. Kirouac
Cole Zmurchok
Denise Morris
ArticleOpen Access18 Mar 2024
Forum on immune digital twins: a meeting report

Reinhard Laubenbacher
Fred Adler
Tjalf Ziemssen
PerspectiveOpen Access16 Feb 2024
MarkerMap: nonlinear marker selection for single-cell studies

Wilson Gregory
Nabeel Sarwar
Bianca Dumitrascu
ArticleOpen Access14 Feb 2024

Announcements

npj Systems Biology and Applications Journal Metrics

npj Systems Biology and Applications has a 2-year impact factor of 4.0 (2022), article downloads of 224,006 (2022) and 8 days from submission to first editorial decision (2022).
Call for papers on phenotypic landscapes of biological

This collection calls for papers combining omics datasets to unravel the mechanisms of phenotypic stability associated with the topology and function of biological networks.
Call for papers: Methodological developments in systems

This collection calls for papers that focus on the latest computational and modelling developments in systems biology research.

Open for submissions
Call for papers on mathematical oncology

Mathematical and computational oncology are rapidly emerging as critical areas of research that aim to understand the intricate and complex nature of cancer. We invite submissions from both early career and senior researchers, and particularly encourage research with high translational value.

Open for submissions

Browse articles

EpiScan: accurate high-throughput mapping of antibody-specific epitopes using sequence information

Chuan Wang
Jiangyuan Wang
Taijiao Jiang
ArticleOpen Access09 Sept 2024
Codon usage and expression-based features significantly improve prediction of CRISPR efficiency

Shaked Bergman
Tamir Tuller
ArticleOpen Access03 Sept 2024
A Boolean model explains phenotypic plasticity changes underlying hepatic cancer stem cells emergence

Alexis Hernández-Magaña
Antonio Bensussen
Elena R. Álvarez-Buylla
ArticleOpen Access02 Sept 2024
Network topology and interaction logic determine states it supports

Tomáš Gedeon
Review ArticleOpen Access28 Aug 2024
Recovering biomolecular network dynamics from single-cell omics data requires three time points

Shu Wang
Muhammad Ali Al-Radhawi
Eduardo D. Sontag
ArticleOpen Access27 Aug 2024
Constraint-based modelling predicts metabolic signatures of low and high-grade serous ovarian cancer

Kate E. Meeson
Jean-Marc Schwartz
ArticleOpen Access24 Aug 2024
SignalingProfiler 2.0 a network-based approach to bridge multi-omics data to phenotypic hallmarks

Veronica Venafra
Francesca Sacco
Livia Perfetto
ArticleOpen Access23 Aug 2024
Assessing structural uncertainty of biochemical regulatory networks in metabolic pathways under varying data quality

Yue Han
Mark P. Styczynski
ArticleOpen Access22 Aug 2024
Integrated-omics analysis with explainable deep networks on pathobiology of infant bronchiolitis

Tadao Ooka
Naoto Usuyama
Kohei Hasegawa
ArticleOpen Access22 Aug 2024

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Science jobs

2024 Recruitment notice Shenzhen Institute of Synthetic Biology: Shenzhen, China

The wide-ranging expertise drawing from technical, engineering or science professions...

Shenzhen,China

Shenzhen Institute of Synthetic Biology
Assistant Professor in Forest Genetics

Assistant Professor position in Forest Genetics with focus on genetic biodiversity in relation to forestry at Umeå Plant Science Centre

Umeå (Kommun), Västerbotten (SE)

Swedish University of Agricultural Sciences (SLU)
Faculty Positions in School of Engineering, Westlake University

The School of Engineering (SOE) at Westlake University is seeking to fill multiple tenured or tenure-track faculty positions in all ranks.

Hangzhou, Zhejiang, China

Westlake University
13 PhD Positions at Heidelberg University

GRK2727/1 – InCheck Innate Immune Checkpoints in Cancer and Tissue Damage

Heidelberg, Baden-Württemberg (DE) and Mannheim, Baden-Württemberg (DE)

Medical Faculties Mannheim & Heidelberg and DKFZ, Germany
Assistant Professor - Plant Single Cell Biology

The Department of Cell & Systems Biology in the Faculty of Arts & Science at the University of Toronto invites applications for a full-time tenure ...

Toronto (City), Ontario (CA)

University of Toronto

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