npj Systems Biology and Applications

npj Systems Biology and Applications

Multi-omics peripheral and core regions of cancer

Featured

Fluxomics reveals cellular and molecular basis of increased renal ammoniagenesis

Liliane Mpabanzi
Jessica Wainwright
Zita Soons
Article Open Access 20 Dec 2022
Protein painting reveals pervasive remodeling of conserved proteostasis machinery in response to pharmacological stimuli

Dezerae Cox
Angelique R. Ormsby
Danny M. Hatters
Article Open Access 28 Nov 2022

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npj Systems Biology and Applications Journal Metrics

npj Systems Biology and Applications has a 2-year impact factor of 4.671 (2021), article downloads of 227,479 (2021) and 9 days from submission to the first editorial decision (2021).
Nobel Turing Challenge: an ultimate grand challenge

The challenge: to develop a highly autonomous AI system that can perform top-level science, indistinguishable from that produced by the best human scientists

Browse articles

Understanding repertoire sequencing data through a multiscale computational model of the germinal center

Rodrigo García-Valiente
Elena Merino Tejero
Antoine H. C. van Kampen
Article Open Access 16 Mar 2023
Optimization of nutrient utilization efficiency and productivity for algal cultures under light and dark cycles using genome-scale model process control

Chien-Ting Li
Richard Eng
Michael J. Betenbaugh
Article Open Access 15 Mar 2023
MorphoSim: an efficient and scalable phase-field framework for accurately simulating multicellular morphologies

Xiangyu Kuang
Guoye Guan
Lei Zhang
Article Open Access 17 Feb 2023
Systematic analysis of negative and positive feedback loops for robustness and temperature compensation in circadian rhythms

Suchana Chakravarty
Christian I. Hong
Attila Csikász-Nagy
Article Open Access 11 Feb 2023
Integration of single sample and population analysis for understanding immune evasion mechanisms of lung cancer

Xiong Li
Xu Meng
Juan Zhou
Article Open Access 10 Feb 2023
Design principles of improving the dose-response alignment in coupled GTPase switches

Lingxia Qiao
Pradipta Ghosh
Padmini Rangamani
Article Open Access 31 Jan 2023
Metabolic modelling of the human gut microbiome in type 2 diabetes patients in response to metformin treatment

Bouchra Ezzamouri
Dorines Rosario
Saeed Shoaie
Article Open Access 21 Jan 2023
Position-dependent effects of RNA-binding proteins in the context of co-transcriptional splicing

Timur Horn
Alison Gosliga
Stefan Legewie
Article Open Access 18 Jan 2023
Predicting stress response and improved protein overproduction in Bacillus subtilis

Juan D. Tibocha-Bonilla
Cristal Zuñiga
Karsten Zengler
Article Open Access 27 Dec 2022

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Baylor College of Medicine (BCM)
Houston, United States
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Johns Hopkins University School of Medicine (JHUSOM), JHU
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