About the Editors
Dr. Larry Norton is a board-certified medical oncologist with broad interests in cancer prevention, diagnosis and treatment. His research concerns the basic biology of cancer, the mathematics of tumor causation and growth and the development of approaches to better diagnosis, prevention and drug treatment of the disease. He is involved in many areas of research including identifying the genes that predispose people to cancer or that cause cancer, developing new drugs, monoclonal antibodies that target growth factor receptors and vaccines. A major milestone in his research career was the development of an approach to therapy called "dose density," or "sequential dose density."
Jorge S. Reis-Filho, MD, PhD
Director of Experimental Pathology
Memorial Sloan Kettering Cancer Center
Jorge Reis-Filho is an affiliate member of the Human Oncology and Pathogenesis Program and the Computational Biology Center. Dr. Reis-Filho's research program focuses on the development of an integrated morphological and molecular classification for breast cancers by focusing on special histological types and the identification of novel therapeutic targets for specific subgroups of breast cancer patients, through an integrative analysis of data derived from pathology, massively parallel sequencing and functional genomics.
Zoltan Szallasi, MD
Asst. Prof. of Pediatrics
Harvard Medical School
Zoltan Szallasi, MD is a senior research scientist in the Computational Health Informatics Program, at Children’s Hospital, Boston, Harvard Medical School. Dr. Szallasi's group has been applying genomics to characterize key cancer associated biological processes. His main work is focusing around detecting and quantifying DNA repair deficiencies in breast cancer and other solid tumors using next generation sequencing data. The main goal of this work is to enable synthetic lethality driven cancer therapies that target aberrations in specific DNA repair pathways such as homologous recombination or nucleotide excision repair.
Neil M. Iyengar, MD
Assistant Attending Physician, Breast Medicine Service/Department of Medicine
Memorial Sloan Kettering Cancer Center
Dr. Iyengar leads a research program focused on methods to improve cardiometabolic health as a strategy to reduce breast cancer risk and improve response to cancer therapy. His research also investigates the use of drugs that treat metabolic disorders, such as diabetes and obesity, to improve the effectiveness of cancer therapies. Dr. Iyengar leads the Optimal Living Program, a novel care model that aims to translate research findings from lifestyle intervention trials into clinical practice during and after cancer therapy.
Ian E. Krop, MD, PhD
Associate Chief, Division of Breast Oncology, Dana-Farber Cancer Institute
Associate Professor of Medicine, HMS
Dana-Farber Cancer Institute/Harvard Medical School
Dr. Krop is a translational investigator focused on the development of novel molecularly targeted therapies and immunotherapies for breast cancer, and elucidating the mechanisms of resistance to these treatments. The majority of his effort is concentrated in the area of HER2+ breast cancer. He was a leader in the development of the antibody-drug conjugates trastuzumab emtansine (T-DM1) and trastuzumab deruxtecan.
Sherene Loi, MD, PhD
Prof. of Cancer Therapeutics
University of Melbourne
Dr. Loi is a clinician scientist and medical oncologist specializing in the treatment of breast cancer. Her research at the Peter MacCallum Cancer Centre focuses on understanding the genomic and immune interface in breast cancer using preclinical models, human breast cancer samples as well as high resolution genomic technologies. She is also involved in developing novel immunotherapy combinations. She is co-chair of the international TILs working group in breast cancer, which resulted in development of an immune biomarker specifically for use in breast cancer patients.
Caterina Marchio, PhD
Assoc. Prof. of Pathology
University Turin at Candiolo Cancer Institute - FPO IRCCS
Caterina Marchiò leads the Research Program of the Pathology Unit at the Candiolo Cancer Institute where her research interests span from histopathogenesis of breast carcinomas to molecular pathology of special histologic types of breast cancer and genetics of HER2-positive and HER2-low carcinomas. She is actively involved in the standardization of preanalytical conditions in Pathology to ensure optimal tissue preservation and quality of DNA, RNA and antigens to guarantee the success of precision medicine.
Steffi Oesterreich, PhD
The Shear Family Foundation Chair in Breast Cancer Research
Prof. of Pharmacology and Chemical Biology
University of Pittsburgh
Pittsburgh, PA, USA
Dr Oesterreich is a translational breast cancer researcher. Her work focuses on endocrine resistance, invasive lobular breast cancer and metastases. She is Co-Leader of the Cancer Biology Program at UPMC Hillman Cancer Center, and Co-Director of the Womens Cancer Research Center at UPMC HCC/Magee Womens Research Institute in Pittsburgh, PA
Andrea L. Richardson, MD, PhD
Assoc. Prof. of Pathology
Johns Hopkins Medicine
Baltimore, MD, USA
Andrea Richardson M.D. Ph.D. is Associate Professor and Director of Pathology for the Johns Hopkins Medicine National Capital Region where she is a practicing physician and translational breast cancer scientist. Her research has focused on characterizing the molecular aberrations in subtypes of breast cancer important for pathogenesis, tumor progression, and tumor response to therapy. Through genomic analysis of tissues, her laboratory identified a DNA damage signature termed NtAI that is high in BRCA-like cancers and predicts for response to certain drugs. Myriad has developed this predictor into a commercial test (MyChoice CDx) which is now available for clinical use. Her current research expands on these findings to study the role of mutational signatures in tumors and cell line models to predict for DNA damage repair defects and drug sensitivity.
Fernando Schmitt, MD, PhD
Prof. of Pathology
Medical Faculty of Porto University
Professor of Pathology at the University of Porto, Director of RISE (Clinical and Translational Research Network of the Medical Faculty) and Head of Molecular Pathology at IPATIMUP.Past-President of the International Society of Breast Pathology and General Secretary and President-elect of the International Academy of Cytology (IAC). He has authored more than 500 papers in peer-review journals, 33 book chapters and he is editor of 6 books. He is widely considered a world-leading expert in cytopathology and breast cancer. His research work is on breast cancer, with emphasis on molecular markers and therapeutic targets.
Joseph A. Sparano, MD
Prof. of Medicine & Obstetrics, Gynecology and Women's Health
Albert Einstein College of Medicine
Joseph Sparano's research has focused on developmental therapeutic approaches for breast cancer, lymphoma and HIV-associated cancers, and therapeutic application of molecular profiling in cancer. Dr. Sparano serves as Vice Chair of the ECOG-ACRIN Research Group and Vice Chair of the AIDS Malignancy Consortium.
Cliff Hudis is a medical oncologist with research interests in all areas of care related to breast cancer. A particular research focus of his team is the interplay between inflammation, obesity and breast cancer, and they are now actively translating their findings into clinically relevant trials with the potential to reduce the global burden of breast and other cancers.
Editorial Board Members
Kathy S. Albain, MD, FACP Loyola University Chicago, IL, USA
Sunil Badve, MD Indiana University School of Medicine, Indiana, USA
Gabor Balázsi, PhD Stony Brook University, New York, USA
John M.S. Bartlett, PhD Ontario Institute for Cancer Research Toronto, Ontario, Canada
Debra L. Barton, PhD University of Michigan, MI, USA
Powel H. Brown, MD University of Texas, MD Anderson Cancer Center Houston, Texas, USA
Maggie Cheang, MD The Institute of Cancer Research Surrey, London, UK
Lewis A. Chodosh, MD University of Pennsylvania, Pennsylvania, USA
Carsten Denkert, MD, PhD Charité Universitätsmedizin Berlin, Berlin, Germany
Matthew J. Ellis, BSc, MB, BChir, PhD, FRCP Baylor College of Medicine, Texas, USA
Prudence A. Francis, MD Peter MacCallum Cancer Centre, Melbourne, Australia
Benita S. Katzenellenbogen, MD University of Illinois Urbana-Champaign, Illinois, USA
Seema A. Khan, MD Northwestern University Evanston, Illinois, USA
Adrian V. Lee, PhD University of Pittsburgh, Pennsylvania, USA
Ephrat Levy-Lahad, MD Shaare Zedek Medical Center, Jerusalem, Israel
Caterina Marchio, PhD University of Turin, Turin, Italy
Stefan Michiels, PhD Université Paris-Sud Paris, Paris, France
Kenneth Offit, MD, MPH Memorial Sloan Kettering Cancer Center, New York, USA
Edith A. Perez, MD Mayo Clinic Jacksonville, Florida, USA
Stuart J. Schnitt, MD Brigham and Women's Hospital, Massachusetts, USA
Valerie Speirs, PhD Leeds Institute of Cancer & Pathology, Leeds, United Kingdom
Anne Vincent-Salomon, PhD Institut Curie Paris, Paris, France
Geoffrey M. Wahl, MD Salk Institute La Jolla, California, USA
Jedd Wolchok, MD, PhD Memorial Sloan Kettering Cancer Center, New York, USA
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