Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
Precision placement and transport is crucial for high-throughput autonomous molecular sorting and detection. Take nanopore sequencing as an example. The delivery of DNA molecules towards a nanopore determines the throughput and precision of the measurement. Now, using all-atom molecular dynamics, Shankla et al. find that, subject to force, molecules are more likely to move down a step defect than up the defect and are more likely to be displaced along the step defect line. The cover art depicts the tendency of adsorbed DNA molecules to move down and along the defect edge of graphene surface-step defects that separate multilayer domains. The principle can be used to guide the delivery of molecules in various technological processes.
The trade-off between necessary scientific communication and the associated CO2 footprint asks for a thorough reconsideration of our travelling habits, new institutional travelling policies and for alternative approaches to interaction with colleagues and peers.
Coherent ultrafast spectroscopy of nanofocused plasmonic pulses strengthens the nonlinear response in graphene, highlighting the origin of a new general phenomenon.
A scalable manufacturing process for complex, high-quality superconductor/topological insulator structures could, in future, enable the production of topological quantum computation architectures.
While heating a catalyst causes growth of nanoparticles through Ostwald ripening, repeated on/off high-temperature shockwaves can reverse the process, converting the nanoparticles into stable single-atom catalysts.
In a ferromagnetic layer, an electric current parallel to the magnetization generates opposite spin–orbit torques on the two surfaces of the magnetic film, which is attributed to the generation of spin currents with a spin polarization transverse to the magnetization within the ferromagnet.
An in situ only fabrication process for networks of topological insulator–superconductor Josephson junctions with high interface transparency is introduced, which holds some potential for the production of future topological quantum computing networks.
Local changes of the Coulomb interaction due to external dielectric environment fluctuations present a new type of disorder in monolayer transition-metal dichalcogenides.
A repeated on–off high-temperature shockwave is shown to be a generalizable way of efficiently synthesizing and stabilizing single atoms at high temperatures.
Subject to force, molecules are more likely to move down a step defect than up the defect and are even more likely to be displaced along the step defect line.
Automated 3D design produces rapid and near-atomically accurate predictions of RNA tertiary structure as well as the ability to generate complex RNA machines such as functional single-stranded tethered ribosomes, and enhancement of the binding properties of small-molecule RNA aptamers.
Glutathione-mediated biotransformation in the liver sinusoids could modulate nanoparticle transport in vivo, which can be exploited to design nanoparticles with enhanced tumour targeting and reduced non-specific accumulation in the body.
Catalytic gold nanoclusters that respond to protease activity in vivo and are excreted in urine can offer a quick colorimetric tool for disease detection in resource-limited settings.
Combination of dendritic-cell-targeted nanovaccines with a myeloid-derived suppressor cell inhibitor and immune checkpoint modulators expands the host antitumour immune cells, restricts tumour growth and prolongs survival in orthotopic melanoma models.