Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
The resistance of bacteria against antibiotics represents one of the biggest issues of the 21st century. Nanotechnologies applying silver nanoparticles are considered an emerging tool in antimicrobial therapies as their action has not yet been associated with any resistance. A. Panáček, L. Kvítek, R. Zbořil and co-workers have now discovered that gram-negative bacteria repeatedly exposed to silver nanoparticles can develop resistance to their antibiotic activity. The cover is an artist’s rendition of the resistance mechanism based on the production of flagellin — an adhesive protein of bacterial flagellum, which causes nanoparticles’ aggregation and thereby eliminates their antibacterial effect. Importantly, the resistance evolves without any genetic changes and can be overcome by the addition of pomegranate rind extract inhibiting the flagellin production in bacteria.
Chris Toumey revisits the 2003 exchange of opinions between Eric Drexler and Richard Smalley, which was one of the most colourful disagreements in the history of nanotechnology.
The microstate of geometrically frustrated two-dimensional arrays of strongly interacting nanomagnets is controlled by means of topological defect-driven magnetic writing, to the extent that elusive configurations such as the ground state and negative-temperature states are realized.
Negative capacitance effect in a ferroelectric-based gate stack provides an effective solution for hysteresis-free steep-slope operation in a MoS2 field-effect transistor.
A terbium-based molecular magnet, containing four nuclear quantum states, or a qudit, experimentally validates the Grover algorithm for database searches.
This Perspective describes the fundamental principles of nano-opto-electo-mechanical systems and their applications in communication, sensing and signal transduction.
Electric polarization is induced in the binary rock salt layer of an ultrathin insulating heterostructure on a metal electrode, and its hysteretic reversal is demonstrated using a combination of atomically resolved scanning probe microscopies.
A field-effect MoS<Subscript>2</Subscript> transistor with a negative capacitor in its gate shows stable, hysteresis-free performance characterized by a sub-thermionic sub-threshold slope.
Advanced nanoengineering of small-period AG lattices enables the observation of a vanishing density of states that suggests the presence of massless Dirac fermions.
Observation of an efficient out-of-plane energy transfer channel in van der Waals heterostructures, where charge carriers in graphene couple to hyperbolic phonon–polaritons on a picosecond timescale.
Boron-nitride-supported graphene transistors show prominent current and noise temperature saturation due to hyperbolic phonon emission by non-equilibrium electron–hole pairs.
Elusive magnetic configurations of geometrically frustrated artificial kagome dipolar spin ices are realized by means of topological defect-driven magnetic writing.
Gram-negative bacteria exposed to subinhibitory concentrations of silver nanoparticles can develop resistance to their antibiotic activity due to the production of flagellin, an adhesive protein of the bacterial flagellum, which causes the aggregation of silver nanoparticles.
The combination of paclitaxel and the antiangiogenic agent BIBF 1120, loaded into nanoparticles, induces synthetic lethality in endometrial cancers with specific mutations in the tumour suppressor p53, providing the first step towards personalized medicine for endometrial cancer.
RNA nanotechnology is utilized for directional control by altering the orientation of arrow-shaped RNAs for either ligand-display on extracellular vesicle or to regulate intracellular trafficking of siRNA or miRNA in cancer treatment.