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Volume 11 Issue 8, August 2016

The neuronal membrane progressively collects postsynaptic potential signals from neighbouring neurons and integrates them until a threshold value is reached, resulting in an action potential being fired. Tomas Tuma, Evangelos Eleftheriou and colleagues have now reproduced this integrate-and-fire functionality by means of a single nanodevice working on a typical timescale of a nanosecond. To this end, they exploit the reversible transition between amorphous and crystalline states of chalcogenide-based phase-change materials. These devices display intrinsically stochastic dynamics, analogous to biological neurons, making them extremely appealing for applications in the field of neuromorphic computation.

Article p693; News & Views p655

IMAGE: XVIVO SCIENTIFIC ANIMATION

COVER DESIGN: BETHANY VUKOMANOVIC

Correction

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Editorial

  • Advances in nanotechnology and materials science suggest that a paradigm shift in computation may be closer than we think.

    Editorial
  • The uncertainty created by the result of the Brexit referendum will be damaging for science in the UK.

    Editorial
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Research Highlights

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News & Views

  • Induced progressive crystallization in chalcogenide-based materials can be used to closely mimic neuronal functions, opening new paths to neuromorphic computing.

    • C. David Wright
    News & Views
  • Measuring changes in the isotopic composition of silver offers clues on how silver nanoparticles are transformed in the environment.

    • Frank Vanhaecke
    News & Views
  • The ambiguous barrier mechanism of nuclear pore complexes has now been resolved through structural analysis with high-speed atomic force microscopy.

    • Victor Shahin
    News & Views
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Review Article

  • Semiconductor nanocrystals offer an enormous diversity of device applications that have been potentially limited by intermittent fluorescence intensity or 'blinking' dynamics. However, recent progress in both experiment and theory suggest a more promising outlook.

    • Alexander L. Efros
    • David J. Nesbitt
    Review Article
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Letter

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Article

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Erratum

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In the Classroom

  • Hybrid training in clinical and basic sciences can promote patient-centred discoveries in nanomedicine, says Wen Jiang.

    • Wen Jiang
    In the Classroom
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