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Volume 10 Issue 9, September 2015

The DNA origami technique — in which a long strand of DNA is folded into a desired shape with the help of numerous short staple strands — has been used to create a range of 2D and 3D nanostructures. These structures are, however, typically made up of tightly packed parallel DNA helices. Hao Yan, Yan Liu and colleagues have now developed a design strategy for engineering wireframe DNA origami nanostructures that uses multi-arm junction vertices. The technique can be used to construct a variety of complex structures including quasicrystalline 2D patterns and reconfigurable 3D Archimedean solids. The artist’s impression on the cover illustrates some of the 3D wireframe Archimedean solid structures that were created.

Letter p779; News & Views p733

IMAGE: MICHAEL NORTHROP

COVER DESIGN: ALEX WING

Editorial

  • For DNA nanodevices to be deployed in living cells and higher organisms, they need to be biocompatible and inexpensive enough to be produced in large quantities.

    Editorial

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Thesis

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Research Highlights

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News & Views

  • DNA origami nanostructures of unprecedented complexity can be created by finding a DNA strand path through wireframe shapes using an approach based on graph theory.

    • Ebbe Sloth Andersen
    News & Views
  • Arrays of CMOS nanocapacitors, which can operate at high frequencies, can be used to sense beyond the Debye screening length.

    • Sven Ingebrandt
    News & Views
  • The propagation direction of surface plasmon wakes can be controlled by exciting a series of dipoles with different phases along a one-dimensional metamaterial.

    • Hongsheng Chen
    • Zhaoyun Duan
    • Min Chen
    News & Views
  • Low dimensionality in NbSe2 layers enhances the critical temperature for the onset of charge density wave order, up to a temperature of 145 K in the monolayer limit.

    • Matteo Calandra
    News & Views
  • Characterization of a microdisk resonator suggests that it could be used for ultrasensitive mass detection in biological environments.

    • Javier Tamayo
    News & Views
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Perspective

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Review Article

  • This article reviews recent progress in the development of cellular DNA nanotechnology, highlighting key potential applications such as DNA-based imaging probes, smart therapeutics, and drug delivery systems.

    • Yuan-Jyue Chen
    • Benjamin Groves
    • Georg Seelig
    Review Article
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Letter

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Article

  • A monolithic heterostructure nanosheet composed of a ZnCdSSe multi-segment quaternary alloy can simultaneously emit laser light in the red, green and blue.

    • Fan Fan
    • Sunay Turkdogan
    • C. Z. Ning
    Article
  • Miniature optomechanical disks could be used as ultrafast and ultrasensitive fluidic sensors due to the combination of their high-frequency vibrations, small mass and low dissipation in liquids.

    • E. Gil-Santos
    • C. Baker
    • I. Favero
    Article
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In the Classroom

  • Developing soft skills can be an important part of a successful academic career. Elisa De Ranieri shares her views on how students can hone theirs.

    • Elisa De Ranieri
    In the Classroom
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