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Volume 10 Issue 4, April 2015

Peptide self-assembly and structural DNA nanotechnology are two important but distinct branches of bionanotechnology. Ehud Gazit and colleagues have now looked to combine these two fields by exploring the assembly of peptide nucleic acids (PNAs) — short DNA mimics that have an amide backbone. Three guanine-containing di-PNAs — CG, GC and GG — were found to form ordered assemblies, and the crystal structure of GC di-PNA revealed the occurrence of both stacking interactions and Watson–Crick base pairing. The computer-generated image on the cover shows a perspective view of this crystal structure.

Article p353; News & Views p295

CREDIT: ELLA MARUSHCHENKO, SCIENTIFIC ILLUSTRATIONS

COVER DESIGN: KAREN MOORE

Correspondence

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Commentary

  • Tackling the degradation of cultural heritage requires a global effort. We call on all material scientists to develop new nanomaterials and methods for the preservation of artwork.

    • Piero Baglioni
    • Emiliano Carretti
    • David Chelazzi
    Commentary
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Thesis

  • More than a decade after it was first published, Chris Toumey revisits a report from the Royal Society on the opportunities and uncertainties of nanotechnology, and finds that it still has plenty to offer.

    • Chris Toumey
    Thesis
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Research Highlights

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News & Views

  • The four-letter molecular code of DNA and the twenty-letter expression language of peptides have inspired the development of two thriving, but distinct, branches of nanotechnology; a technique that combines the two approaches could lead to robust, scalable materials with unique optoelectronic properties.

    • Rein V. Ulijn
    News & Views
  • By combining the geometric phase with plasmonic metasurfaces, it is possible to make wide-angle holograms with power efficiency of 80% over a broad range of frequencies.

    • Jacob Scheuer
    • Yuval Yifat
    News & Views
  • Calcium and phosphate ions secreted in the intestine form nanoparticles that protect and shuttle protein antigens from the lumen to immune cells in the intestinal wall lining.

    • Johan D. Söderholm
    News & Views
  • The combination of Cerenkov light and nanoparticles now enables photodynamic therapy that does not rely on external light sources.

    • Jan Grimm
    News & Views
  • Multimodal microbubbles exposed to ultrasound shrink to nanoparticles that retain the imaging and drug delivery potential of the parent microbubble.

    • Gregory M. Lanza
    News & Views
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Correction

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Letter

  • Using a metasurface comprising an array of nanorods with different orientations and a backreflector, a hologram image can be obtained in the visible and near-infrared with limited loss of light intensity.

    • Guoxing Zheng
    • Holger Mühlenbernd
    • Shuang Zhang
    Letter
  • A technique based on templated electrochemical synthesis can be used to prepare coaxial nanowires with sub-10 nm resolution in both axial and radial dimensions.

    • Tuncay Ozel
    • Gilles R. Bourret
    • Chad A. Mirkin
    Letter
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Article

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In the Classroom

  • Working in large collaborations can help you understand how nanotechnology is closely related to other fields, explains Elizabeth Huynh.

    • Elizabeth Huynh
    In the Classroom
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