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Plasmonic tunnel junctions integrated with a monolayer semiconductor are found to emit photons with energies exceeding the input electrical potential. This peculiar phenomenon is ascribed to being triggered by inelastic electron tunnelling dipoles inducing optically forbidden transitions in the carrier injection electrode.
A method for overcoming antibiotic resistance uses multimodal nanoparticles that target bacterial defence mechanisms while enhancing the innate immune response.
Antimicrobial resistance is becoming more prevalent. Here the authors use multimodal nanoparticles to modulate the infected microenvironment, recruit neutrophils and alleviate hypoxia to restore neutrophil function, demonstrating therapeutic efficacy against MRSA infections in mice.
A single-walled carbon nanotube spring stores three times more mechanical energy than a lithium-ion battery, while offering wide temperature stability and posing no explosion risk.
A double-blind, randomized, controlled human exposure trial of highly purified and thin nanometre-sized graphene oxide nanosheets shows that acute inhalation of aerosolized nanoparticles is not associated with harmful effects in healthy humans.
Engineering the tunability of protein assembly in response to pH changes within a narrow range is challenging. Here the authors report the de novo computational design of pH-responsive protein filaments that exhibit rapid, precise, tunable and reversible assembly and disassembly triggered by small pH changes.
How can light be efficiently manipulated below the single-pixel level? An answer is now provided using near-field interactions for nanopillars in a metasurface — phase gradients in the gaps between the nanopillars constitute a new degree of freedom that enables efficient wavefront control at the nanoscale.
Robotics and machine learning are combined to predict and prepare a variety of nanocomposite materials with properties mimicking those of various types of plastics, starting from natural building blocks.
A genetically engineered variant of the stimulator of interferon genes (STING) protein is delivered to cancer cells, showing potential for clinical impact.
A distance-based mapping strategy using single-molecule fluorescence resonance energy transfer via DNA eXchange (FRET X) enables full-length fingerprinting of intact protein sequences.
The performance of three-terminal molecular transistors is enhanced through the harnessing of quantum interference in the edges of graphene electrodes.
An experimental demonstration of how destructive quantum interference effects can increase the performance of single-molecule field-effect transistors to reach levels similar to those of nanoelectronic transistors.
Operando transmission electron microscopy imaging reveals that modifying interlayer rotations alters both the spatial arrangement and switching dynamics of polar domains in artificially stacked trilayers of WSe2.
Understanding how cells process nanoparticles is crucial to improve nanomedicine efficacy. Here a genome-wide screening is used to discover proteins that are involved in silica nanoparticle accumulation by cells and shows that different apolipoprotein receptors and proteoglycans mediate their internalization.
Tumour cell behaviour is an underdeveloped target for cancer intervention. Here the authors report on a spatiotemporal interaction between tumour cells and osteoclasts in initial bone metastases and propose a behaviour-targeting therapy with an in situ physical killing strategy.