In 1959 Richard Feynman called for researchers to improve the resolution of the electron microscope, and they have — but resolution is only part of the story.
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Segal, M. Surely you're happy, Mr Feynman!. Nature Nanotech 4, 786–788 (2009). https://doi.org/10.1038/nnano.2009.360
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DOI: https://doi.org/10.1038/nnano.2009.360