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Self-assembly is a powerful technique for controlling the structure and properties of ensembles of inorganic nanoparticles. This article reviews the properties and potential applications of self-assembled structures made from nanoparticles.
Gold nanoparticles can be assembled into ordered arrays through the site-selective deposition of mesoscopic DNA origami onto lithographically patterned substrates and the precise binding of gold nanocrystals to each DNA structure.
The adhesion of single DNA molecules on modified gold surfaces can be adjusted by surface potential, and the desorption forces of these interactions are measured by single-molecule force spectroscopy.
Asymmetric salt concentrations can be used to enhance the capture rate of DNA in solid-state nanopores and detect picomolar solutions of unlabelled DNA.
An atomic force microscope can probe both the surface and subsurface regions of a sample by exploiting nanomechanical coupling between the probe and the sample.
Nanoparticles can be assembled into superlattices and dimer clusters using a reconfigurable DNA device that also allows interparticle distances to be modified, post-assembly, in response to molecular stimuli.
A biosensor containing a microfluidic purification chip that supplies a downstream nanoribbon-detector can detect disease biomarkers in samples of whole blood.
A single dopant atom can dominate the subthreshold behaviour of a field-effect transistor, and this effect is enhanced if the atom is located near a dielectric.
This article reviews the emergence of the atomic force microscope as a tool capable of creating nanostructures at room temperature, one atom at a time.