Review Articles in 2021

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  • Although quantum physics underpins the behaviour of nanoscale objects, its role in nanoscience has been mostly limited to determining the static, equilibrium properties of small systems. This Review describes seminal developments and new directions for the explicit exploitation of quantum coherence in nanoscale systems, a research area termed quantum-coherent nanoscience.

    • Andreas J. Heinrich
    • William D. Oliver
    • Andrea Morello
    Review Article
  • Nanoparticles used for biomedical applications might elicit unexpected adverse or beneficial biological effects unrelated to the function for which they were designed. In this Review, the authors describe some of these ‘yin and yang’ ancillary effects, and discuss their implications for nanomedicine development.

    • Evan P. Stater
    • Ali Y. Sonay
    • Jan Grimm
    Review Article
  • The preparation of a diverse set of 2D materials and their co-integration in van der Waals heterostructures enable innovative material design and device engineering. This Review summarizes recent advances in 2D spintronics and opto-spintronics, the underlying physical concepts and future perspectives of the field.

    • Juan F. Sierra
    • Jaroslav Fabian
    • Sergio O. Valenzuela
    Review Article
  • In this Review the authors discuss the biological role of extracellular vesicles and how they can be applied as drug carriers, focusing on the current state of their manufacturing and existing challenges.

    • Inge Katrin Herrmann
    • Matthew John Andrew Wood
    • Gregor Fuhrmann
    Review Article
  • This Review presents the emerging understanding of the importance of the dynamic and evolving protein corona composition in mediating the fate, transport and biological identity of nanomaterials in the environment. Principles specific to the environment are presented, along with a perspective on next steps toward mechanistic and predictive insights for the next phase of eco-corona studies.

    • Korin E. Wheeler
    • Andrew J. Chetwynd
    • Iseult Lynch
    Review Article
  • This Review provides an overview of four platform technologies that are currently used in the clinic for delivery of nucleic acid therapeutics, describing their properties, discussing technical advancements that led to clinical approval, and highlighting examples of approved genetic drugs that make use of these technologies.

    • Jayesh A. Kulkarni
    • Dominik Witzigmann
    • Roy van der Meel
    Review Article
  • This Review outlines the potential applications of nanotechnology-based treatments for infectious diseases, with a specific focus on the progress and challenges in developing nanomedicines against HIV, tuberculosis and malaria.

    • Ameya R. Kirtane
    • Malvika Verma
    • Giovanni Traverso
    Review Article
  • This Review summarizes the development history of Pt-based nanocatalysts and recent analytical studies to identify the technical issues in the automobile application, proposing promising strategies for overcoming the trade-offs among the efficiency,power density, and durability of polymer electrolyte fuel cells.

    • Kensaku Kodama
    • Tomoyuki Nagai
    • Yu Morimoto
    Review Article
  • This Review discusses the progress and the remaining challenges for the clinical application of nanomaterial-based T-cell immunotherapies.

    • Ningqiang Gong
    • Neil C. Sheppard
    • Michael J. Mitchell
    Review Article