Articles

  • Article |

    An optoelectronic resistive switching memory synaptic device enables the realization of an efficient neuromorphic visual system exhibiting non-volatile optical resistive switching and light-tunable synaptic behaviours.

    • Feichi Zhou
    • , Zheng Zhou
    • , Jiewei Chen
    • , Tsz Hin Choy
    • , Jingli Wang
    • , Ning Zhang
    • , Ziyuan Lin
    • , Shimeng Yu
    • , Jinfeng Kang
    • , H.-S. Philip Wong
    •  & Yang Chai
  • Article |

    Nanopore AFM is used for the stochastic sensing of secreted molecules and the activity of ion channels in arbitrary locations both inside and outside a cell.

    • Morteza Aramesh
    • , Csaba Forró
    • , Livie Dorwling-Carter
    • , Ines Lüchtefeld
    • , Tilman Schlotter
    • , Stephan J. Ihle
    • , Ivan Shorubalko
    • , Vahid Hosseini
    • , Dmitry Momotenko
    • , Tomaso Zambelli
    • , Enrico Klotzsch
    •  & János Vörös
  • Article |

    The combination of two-photon lithography and high-temperature pyrolysis is used to create micro-sized pyrolytic carbon with a compressive strength of 9.79 GPa cm3 g−1. This enables rubber-like behaviour in micropillars, which can sustain compressive strain up to 50%.

    • Xuan Zhang
    • , Lei Zhong
    • , Arturo Mateos
    • , Akira Kudo
    • , Andrey Vyatskikh
    • , Huajian Gao
    • , Julia R. Greer
    •  & Xiaoyan Li
  • Article |

    A zwitterionic camptothecin–polymer conjugate that is enzymatically transformed in a cationic molecule at the tumour periphery penetrates deep into tumours via caveolae-mediated endocytosis and transcytosis, resulting in high anticancer efficiency in vivo.

    • Quan Zhou
    • , Shiqun Shao
    • , Jinqiang Wang
    • , Changhuo Xu
    • , Jiajia Xiang
    • , Ying Piao
    • , Zhuxian Zhou
    • , Qingsong Yu
    • , Jianbin Tang
    • , Xiangrui Liu
    • , Zhihua Gan
    • , Ran Mo
    • , Zhen Gu
    •  & Youqing Shen
  • Article |

    A nanoporous polyimide film filled with a solid polymer electrolyte has high ionic conductivity and high mechanical strength. An all-solid-state battery made with an approximately 10-μm-thick film shows good cyclability at 60 °C and no dendrite formation.

    • Jiayu Wan
    • , Jin Xie
    • , Xian Kong
    • , Zhe Liu
    • , Kai Liu
    • , Feifei Shi
    • , Allen Pei
    • , Hao Chen
    • , Wei Chen
    • , Jun Chen
    • , Xiaokun Zhang
    • , Linqi Zong
    • , Jiangyan Wang
    • , Long-Qing Chen
    • , Jian Qin
    •  & Yi Cui
  • Article |

    Virus nanoparticles can penetrate soil to a depth of 30 cm, thus showing potential to effectively deliver nanopesticides.

    • Paul L. Chariou
    • , Alan B. Dogan
    • , Alexandra G. Welsh
    • , Gerald M. Saidel
    • , Harihara Baskaran
    •  & Nicole F. Steinmetz
  • Article |

    Light scattering spectra are acquired in the near field to map dipole–dipole interactions and extract all their vectorial components with 5-nm spatial resolution.

    • Martin Esmann
    • , Simon Fabian Becker
    • , Julia Witt
    • , Jinxin Zhan
    • , Abbas Chimeh
    • , Anke Korte
    • , Jinhui Zhong
    • , Ralf Vogelgesang
    • , Gunther Wittstock
    •  & Christoph Lienau
  • Article |

    Metallic lithium wets a functionalized mesoporous carbon film to create a self-smoothing anode that, in conjunction with a standard lithium nickel–manganese–cobalt cathode, delivers long cycling life, 350 Wh kg−1 high-energy cells under realistic conditions.

    • Chaojiang Niu
    • , Huilin Pan
    • , Wu Xu
    • , Jie Xiao
    • , Ji-Guang Zhang
    • , Langli Luo
    • , Chongmin Wang
    • , Donghai Mei
    • , Jiashen Meng
    • , Xuanpeng Wang
    • , Ziang Liu
    • , Liqiang Mai
    •  & Jun Liu
  • Article |

    Current pulses of 105 A cm−2 can control the orientation of 100-nm-wide stripe domains in La0.67Sr0.33MnO3 and spin waves of 10 GHz can propagate along these domains with a group velocity of 2.6 km s−1.

    • Chuanpu Liu
    • , Shizhe Wu
    • , Jianyu Zhang
    • , Jilei Chen
    • , Jinjun Ding
    • , Ji Ma
    • , Yuelin Zhang
    • , Yuanwei Sun
    • , Sa Tu
    • , Hanchen Wang
    • , Pengfei Liu
    • , Chexin Li
    • , Yong Jiang
    • , Peng Gao
    • , Dapeng Yu
    • , Jiang Xiao
    • , Rembert Duine
    • , Mingzhong Wu
    • , Ce-Wen Nan
    • , Jinxing Zhang
    •  & Haiming Yu
  • Article |

    Lithium transition metal oxide cathodes can degrade under high-voltage conditions by a redox mechanism by which oxygen vacancies form at the surface and migrate towards the bulk.

    • Pengfei Yan
    • , Jianming Zheng
    • , Zhen-Kun Tang
    • , Arun Devaraj
    • , Guoying Chen
    • , Khalil Amine
    • , Ji-Guang Zhang
    • , Li-Min Liu
    •  & Chongmin Wang
  • Article |

    A specifically designed family of synthetic lipids exhibits unique liquid-crystalline behaviour at low temperature, enabling maintenance of amorphous water down to about 10 K due to nanoconfinement.

    • Livia Salvati Manni
    • , Salvatore Assenza
    • , Michael Duss
    • , Jijo J. Vallooran
    • , Fanni Juranyi
    • , Simon Jurt
    • , Oliver Zerbe
    • , Ehud M. Landau
    •  & Raffaele Mezzenga
  • Article |

    Ionic Coulomb blockade in nanochannels is shown to be a consequence of a second Wien effect, resulting from the dissociation of Bjerrum pairs that are formed under confinement.

    • Nikita Kavokine
    • , Sophie Marbach
    • , Alessandro Siria
    •  & Lydéric Bocquet
  • Article |

    Administration of the clinically approved iron oxide nanoparticle drug ferumoxytol in vitro results in an anti-leukaemia effect and in vivo extended overall survival in part due to the low expression of the iron export protein ferroportin.

    • Vicenta Trujillo-Alonso
    • , Edwin C. Pratt
    • , Hongliang Zong
    • , Andres Lara-Martinez
    • , Charalambos Kaittanis
    • , Mohamed O. Rabie
    • , Valerie Longo
    • , Michael W. Becker
    • , Gail J. Roboz
    • , Jan Grimm
    •  & Monica L. Guzman
  • Article |

    Overcrowded alkene-based motors are made part of the crystalline structure of a metal–organic framework. It is shown that they retain the same rotatory speed and unidirectionality as in solution.

    • Wojciech Danowski
    • , Thomas van Leeuwen
    • , Shaghayegh Abdolahzadeh
    • , Diederik Roke
    • , Wesley R. Browne
    • , Sander J. Wezenberg
    •  & Ben L. Feringa
  • Article |

    A scanning single-electron transistor-based method enables simultaneous visualization of voltage and current density of flowing electrons in two-dimensional systems with high sensitivity and minimal invasiveness

    • Lior Ella
    • , Asaf Rozen
    • , John Birkbeck
    • , Moshe Ben-Shalom
    • , David Perello
    • , Johanna Zultak
    • , Takashi Taniguchi
    • , Kenji Watanabe
    • , Andre K. Geim
    • , Shahal Ilani
    •  & Joseph A. Sulpizio
  • Article |

    Semipermeable proteinosome membranes allow complex DNA message communication through compartmentalization and protect the DNA circuits from degradation in a biological environment.

    • Alex Joesaar
    • , Shuo Yang
    • , Bas Bögels
    • , Ardjan van der Linden
    • , Pascal Pieters
    • , B. V. V. S. Pavan Kumar
    • , Neil Dalchau
    • , Andrew Phillips
    • , Stephen Mann
    •  & Tom F. A. de Greef
  • Article |

    Chitosan-functionalized single-walled carbon nanotubes enable selective gene delivery to the chloroplasts of mature living plants without external mechanical aid.

    • Seon-Yeong Kwak
    • , Tedrick Thomas Salim Lew
    • , Connor J. Sweeney
    • , Volodymyr B. Koman
    • , Min Hao Wong
    • , Karen Bohmert-Tatarev
    • , Kristi D. Snell
    • , Jun Sung Seo
    • , Nam-Hai Chua
    •  & Michael S. Strano
  • Article |

    High aspect ratio nanomaterials enable efficient delivery of DNA into mature plant cells in a species-independent and non-integrating manner for plant genetic engineering applications.

    • Gozde S. Demirer
    • , Huan Zhang
    • , Juliana L. Matos
    • , Natalie S. Goh
    • , Francis J. Cunningham
    • , Younghun Sung
    • , Roger Chang
    • , Abhishek J. Aditham
    • , Linda Chio
    • , Myeong-Je Cho
    • , Brian Staskawicz
    •  & Markita P. Landry
  • Article |

    Sub-micrometre spin waves are excited in anisotropic spin textures and they can propagate as 2D plane waves over several micrometres and as 1D waves along curved domain walls.

    • Volker Sluka
    • , Tobias Schneider
    • , Rodolfo A. Gallardo
    • , Attila Kákay
    • , Markus Weigand
    • , Tobias Warnatz
    • , Roland Mattheis
    • , Alejandro Roldán-Molina
    • , Pedro Landeros
    • , Vasil Tiberkevich
    • , Andrei Slavin
    • , Gisela Schütz
    • , Artur Erbe
    • , Alina Deac
    • , Jürgen Lindner
    • , Jörg Raabe
    • , Jürgen Fassbender
    •  & Sebastian Wintz
  • Article |

    A combination of light-emitting semiconductors and photochromic molecules enables the fabrication of optically switchable organic light-emitting transistors with tunable current and luminance.

    • Lili Hou
    • , Xiaoyan Zhang
    • , Giovanni F. Cotella
    • , Giuseppe Carnicella
    • , Martin Herder
    • , Bernd M. Schmidt
    • , Michael Pätzel
    • , Stefan Hecht
    • , Franco Cacialli
    •  & Paolo Samorì
  • Article |

    Atomically dispersed gold supported by carbon dots amplifies mitochondrial oxidative stress, and leads to irreversible cell damage, inhibiting hepatocellular carcinoma in animal models.

    • Ningqiang Gong
    • , Xiaowei Ma
    • , Xiaoxia Ye
    • , Qunfang Zhou
    • , Xiaoai Chen
    • , Xiaoli Tan
    • , Shengkun Yao
    • , Shuaidong Huo
    • , Tingbin Zhang
    • , Shizhu Chen
    • , Xucong Teng
    • , Xixue Hu
    • , Jie Yu
    • , Yaling Gan
    • , Huaidong Jiang
    • , Jinghong Li
    •  & Xing-Jie Liang
  • Article |

    Dense nanostructuring of hBN-encapsulated graphene enables band structure engineering with distinct magnetotransport signatures and a tunable bandgap.

    • Bjarke S. Jessen
    • , Lene Gammelgaard
    • , Morten R. Thomsen
    • , David M. A. Mackenzie
    • , Joachim D. Thomsen
    • , José M. Caridad
    • , Emil Duegaard
    • , Kenji Watanabe
    • , Takashi Taniguchi
    • , Timothy J. Booth
    • , Thomas G. Pedersen
    • , Antti-Pekka Jauho
    •  & Peter Bøggild
  • Article |

    An electromechanical transducer that integrates a high-frequency phononic crystal with a superconducting microwave circuit enables transduction of hypersonic mechanical motion at the quantum level.

    • Mahmoud Kalaee
    • , Mohammad Mirhosseini
    • , Paul B. Dieterle
    • , Matilda Peruzzo
    • , Johannes M. Fink
    •  & Oskar Painter
  • Article |

    DNA nanodevice can quantitatively map disulfide reduction exclusively in endosomes in C. elegans, by which the location-specific action of proteins can be addressed.

    • Krishna Dan
    • , Aneesh T. Veetil
    • , Kasturi Chakraborty
    •  & Yamuna Krishnan
  • Article |

    Analytical challenges in detecting nanoplastics have hindered the understanding of their behaviour in environmental systems, but these difficulties can be circumvented by synthesizing metal-doped nanoplastics (where the metal can be measured as a proxy for the plastic) to undertake mechanistic investigations of particle fate, transport and biological interactions in lab and pilot-scale studies.

    • Denise M. Mitrano
    • , Anna Beltzung
    • , Stefan Frehland
    • , Michael Schmiedgruber
    • , Alberto Cingolani
    •  & Felix Schmidt
  • Article |

    A nanoparticle self-assembled by a multi-modular peptide and an amphiphilic poloxamine serves as a non-viral gene delivery agent for the long-term expression of CFTR in cell cultures and in animal models of cystic fibrosis.

    • Shan Guan
    • , Antje Munder
    • , Silke Hedtfeld
    • , Peter Braubach
    • , Silke Glage
    • , Longgui Zhang
    • , Stefan Lienenklaus
    • , Anja Schultze
    • , Günther Hasenpusch
    • , Wiebke Garrels
    • , Frauke Stanke
    • , Csaba Miskey
    • , Sarah M. Johler
    • , Yadhu Kumar
    • , Burkhard Tümmler
    • , Carsten Rudolph
    • , Zoltan Ivics
    •  & Joseph Rosenecker
  • Article |

    Nanoparticles used in nanomedicine can induce increased vascular leakiness and therefore accelerate intravasation and extravasation of cancer cells, exacerbating existing metastasis and promoting the appearance of new metastatic sites.

    • Fei Peng
    • , Magdiel Inggrid Setyawati
    • , Jie Kai Tee
    • , Xianguang Ding
    • , Jinping Wang
    • , Min En Nga
    • , Han Kiat Ho
    •  & David Tai Leong
  • Article |

    The temperature-dependent transverse elongation of ferrimagnetic bubbles provides experimental evidence for an evanescent skyrmion Hall effect at zero spin density.

    • Yuushou Hirata
    • , Duck-Ho Kim
    • , Se Kwon Kim
    • , Dong-Kyu Lee
    • , Se-Hyeok Oh
    • , Dae-Yun Kim
    • , Tomoe Nishimura
    • , Takaya Okuno
    • , Yasuhiro Futakawa
    • , Hiroki Yoshikawa
    • , Arata Tsukamoto
    • , Yaroslav Tserkovnyak
    • , Yoichi Shiota
    • , Takahiro Moriyama
    • , Sug-Bong Choe
    • , Kyung-Jin Lee
    •  & Teruo Ono
  • Article |

    Rationally designed polymer vesicles increase cytosolic delivery of cGAMP, activating the STING pathway and increasing the immunogenicity of the tumour microenvironment in in vivo murine models of melanoma and in human metastatic melanoma tissues.

    • Daniel Shae
    • , Kyle W. Becker
    • , Plamen Christov
    • , Dong Soo Yun
    • , Abigail K. R. Lytton-Jean
    • , Sema Sevimli
    • , Manuel Ascano
    • , Mark Kelley
    • , Douglas B. Johnson
    • , Justin M. Balko
    •  & John T. Wilson
  • Article |

    The ordered display of antigen patterns on DNA origami platforms combined with surface plasmon resonance chips allows the investigation of the affinity and kinetics of the antigen–antibody bivalent binding in relation to the antigen distance and antibody flexibility.

    • Alan Shaw
    • , Ian T. Hoffecker
    • , Ioanna Smyrlaki
    • , Joao Rosa
    • , Algirdas Grevys
    • , Diane Bratlie
    • , Inger Sandlie
    • , Terje Einar Michaelsen
    • , Jan Terje Andersen
    •  & Björn Högberg
  • Article |

    A gel with therapeutic nanoformulation that can be sprayed at the tumour resection site after surgery activates immune response in the tissue microenviroment, inhibiting tumour recurrence and potential metastasis.

    • Qian Chen
    • , Chao Wang
    • , Xudong Zhang
    • , Guojun Chen
    • , Quanyin Hu
    • , Hongjun Li
    • , Jinqiang Wang
    • , Di Wen
    • , Yuqi Zhang
    • , Yifei Lu
    • , Guang Yang
    • , Chen Jiang
    • , Jun Wang
    • , Gianpietro Dotti
    •  & Zhen Gu
  • Article |

    A nanotweezer system based on dielectrophoresis can trap, manipulate and extract biomolecules and organelles in living cells at physiological conditions with high spatiotemporal resolution and minimal invasiveness.

    • Binoy Paulose Nadappuram
    • , Paolo Cadinu
    • , Avijit Barik
    • , Alexander J. Ainscough
    • , Michael J. Devine
    • , Minkyung Kang
    • , Jorge Gonzalez-Garcia
    • , Josef T. Kittler
    • , Keith R. Willison
    • , Ramon Vilar
    • , Paolo Actis
    • , Beata Wojciak-Stothard
    • , Sang-Hyun Oh
    • , Aleksandar P. Ivanov
    •  & Joshua B. Edel
  • Article |

    A DNA-based nanosensor that simultaneously measures pH and chloride concentrations can chemically resolve different subpopulations of lysosomes in live cells derived from healthy individuals and patients with Niemann–Pick disease.

    • KaHo Leung
    • , Kasturi Chakraborty
    • , Anand Saminathan
    •  & Yamuna Krishnan