Browse Articles

Nanofibre lung injury has previously been linked to the leakage of reactive oxygen and nitrogen species in frustrated phagocytosis. Here the authors use a nanosensor to demonstrate, map and track the generation of reactive species during the frustrated phagocytosis of model glass nanofibres.

Here, 3D nanofabrication and elasticity programming of monolithic soft microrobots equipped with magnetic springs with strain response at piconewton forces capable of deformation on micrometre length scales is demonstrated for applications in cell force sensing, cell manipulation and soft actuation.

The Review discusses the state-of-the-art polymer nanocomposites from three key aspects: dipole activity, breakdown resistance and heat tolerance for capacitive energy storage applications.

Chitosan/glucose co-polymers encapsulating silver sulfide quantum dots can be used to improve oral delivery of insulin in different animal models without hypoglycaemic incidents.

An atomically thin indium tin oxide film in the form of a quantum well exhibits a χ² of ~1,800 pm V^–1. Theoretical calculations point to an asymmetric electronic interband transition resonance as the reason for this large χ² value.

Insulin injections are not ideal and have an increased risk of hypoglycaemia. A preferable oral formulation based on silver sulfide quantum dots coated with a chitosan/glucose polymer is discussed, which has controlled insulin release and reduced risk of hypoglycaemia, and demonstrates applications in rodent and non-human primate models.

Organic and inorganic nanoparticles have different clearance mechanisms from the brain resulting in different biological fates and retention times.

Nanoparticle clearance is critical for safety and therapeutic applicability. Here the authors report the modulatory role of microglial extracellular vesicles on the brain clearance of organic and inorganic nanoparticles and provide a strategy to control their intracerebral fate.

Electrochemical carbon dioxide (CO₂) reduction in acid with a nano-structured tandem catalyst achieves high single-pass conversion efficiency and selectivity to useful C–C coupled products, bringing the process closer to commercial viability.

Nanoparticles naturally accumulate in the liver; this can be a major limitation to any therapy needing delivery to other organs or tissues. Here the authors review the reason for predominant liver uptake and explore different strategies used to target non-viral gene delivery nanoparticles to other organs and tissues.

Conserved regions of the circular DNA sequence of the M13mp18 bacteriophage, which is used as a scaffold for DNA origami construction, are targeted with specific hybridization-chain-reaction probes. The probes enable sensitive detection of DNA origami nanostructures in cells, organoids and tissues to assess their biodistribution and stability.

Using fluorinated elastomers in the fabrication of soft neural probes is shown to enhance spatiotemporal recording capability at single-neuron resolution within the central nervous system of rodents. Other soft encapsulation materials could be similarly engineered for high-resolution, long-lasting bioelectronics.

Fluorinated elastomers as photoresists in the fabrication of soft neural probes are used to enhance the spatiotemporal recording capability at single-neuron resolution within the central nervous system of rodents.

A biohybrid, leaf-spring design of DNA origami functions as a pulsating nanoengine that exploits the DNA-templated RNA transcription mechanism while consuming nucleoside triphosphates as fuel. The nanoengine also drives a nanomechanical follower structure.

Directionality of nonlinear emission from a dielectric metasurface is controlled by fine-tuning the relative time delay and polarization of two pulsed pump beams.

Electric field tunable interlayer excitons in a van der Waals bilayer emit at an energy of twice the band gap.

This Perspective discusses the current understanding of extracellular vesicles within the context of their movement into and out of blood circulation, with an outlook on leveraging extracellular vesicle nanobiology for mechanistic insights as well as diagnostic and nanotherapeutic applications in both physiological and pathological contexts.

Graphene multistacks with four or five layers show the signature of correlated electronic states both in and out of a magnetic field.

This year’s Nobel Prize in Chemistry recognizes a milestone for the entire nanotechnology field.

Using hydrogel nanovials to capture single mesenchymal stromal cells and their growth factor secretions, the authors link cell secretion to the transcriptome for thousands of cells, SEC-seq, enabling the study of secretion-associated cell states and mechanisms in therapeutic cell types.