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Professor Louis Brus of Columbia University tells Nature Nanotechnology about his first encounter with the world of colloidal quantum dots, the beginning of a journey that has earned him this year’s Nobel Prize in Chemistry (together with Aleksey Yekimov and Moungi Bawendi). He also offers insightful advice to young scientists along the way.
The interference between two frequency-degenerate upconversion processes enables a metasurface-based, all-optical routing by controlling the phase delay between pump beams.
The level of immune response in cancer vaccines can limit application. Here, an immune mobilization strategy, using bacteria-derived nanovesicles, enhances therapeutic outcomes of tumour vaccination by stimulating interleukin-1β secretion to elicit trained immunity with lineage shifts and epigenetic changes in myeloid progenitor pools.
High-energy interlayer excitons in van der Waals semiconducting transition metal dichalcogenides lie far above the bandgap and emit in the ultraviolet range.
Resonant laser excitation is used to control the charge states of colour centre clusters in diamond with sub-diffraction resolution. These states are long-lived and can be read out non-destructively with low energy consumption.
Ion–ion interactions are crucial to the functioning of biological and artificial ion channels. Here the authors reveal that hydrated alkali metal ions can form one-dimensional closely packed chain structures at charged surfaces to facilitate ion transport.
Combined theoretical and experimental efforts provide systematic insights into the origin of self-switchable conductivity in layered semiconductor ferroelectrics. These mechanistic findings may enable advanced logic-in-memory devices.
To determine the physiologically relevant oligomeric form of membrane proteins is extremely challenging. Now an elegant method of counting the oligomers in membrane proteins in near-native states is presented, using photobleaching and nanodiscs formed directly from cellular membranes.
Native-nanoBleach, a single-molecule imaging technique with a spatial resolution of ~10 nm, quantifies the oligomeric distribution of membrane proteins directly from native membranes at endogenous expression levels with their proximal native membrane environment using amphipathic copolymer nanodiscs.
Mechanistic origins of force stability and bond kinetics of interaction of the receptor-binding domain from the SARS-CoV-2 spike protein with angiotensin-converting enzyme 2, a key selection factor for mutations, are revealed at the single-molecule resolution using magnetic tweezers and molecular dynamics simulations.
The development of a tandem catalyst, consisting of two distinct nanoscale-engineered layers, enables efficient multicarbon production with high CO2 utilization in an acidic CO2 electroreduction environment.
Stacking graphene in the rhombohedral order to the tetralayer yields stronger Coulomb interactions, which results in insulating and metallic states with spontaneous symmetry breaking in spin, valley and layer degrees of freedom.
Catalytic metals dissolved in liquid gallium remain atomically dispersed and dynamically active. The configurational dynamics of the metal atoms enables them to adopt a specific configurational alignment with the reactants to facilitate selective propylene synthesis from two different hydrocarbon feedstocks.
Nebulized mRNA delivery has broad therapeutic potential but has proven challenging. Here, the authors report on a modified lipid nanoparticle with improved conditions to allow nebulization and demonstrate its application for delivering mRNA to the lungs.
Catalytic metals dissolved in a liquid gallium solvent remain atomically dispersed. Alignments among the liquid atoms and reactants facilitate selective propylene synthesis from various hydrocarbon feedstocks.
