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  • This Review provides a framework for processing multidimensional vision information at the sensory level and illustrates the working mechanisms as well as design principles of hardware implementations.

    • Zhaoqing Wang
    • Tianqing Wan
    • Yang Chai
    Review Article
  • Inactivating hyperregulated metabolic pathways in cancer is used in the clinic to slow cancer progression. Here the authors show that l-tyrosine can reactivate melanogenesis in melanoma cells, resulting in suppression of cancer growth and production of melanin, which can be used as an additional photothermal therapy agent for melanoma eradication.

    • Yang Chen
    • Chaochao Wang
    • Wenbo Bu
  • A room-temperature polaritonic valley Hall topological insulator has been developed by integrating topological photonics with perovskite-embedded optical cavities, for protected optical signal propagation along pre-designed paths.

    • Helgi Sigurðsson
    • Barbara Piętka
    News & Views
  • Chiral crystals are sought after for their ability to tune the polarization of light. Now, multiwalled boron nitride nanotubes (BNNTs) are shown to be promising chiral crystals with coherently stacked structures, wherein the component tubes display mono-chirality, homo-handedness and unipolarity. This unique architecture endows BNNTs with strong optical nonlinearity and a chiral geometry-dependent chiroptical response.

    Research Briefing
  • Combining single-molecule Förster resonance energy transfer (FRET) and fluorescence lifetime information inside an anti-Brownian electrokinetic (ABEL) trap makes it possible to distinguish dozens of biomolecules in a sample mixture. This method enables extensive barcoding of biomolecules with a minimal set of chemical components and opens up a path toward biomolecule quantification in complex mixtures.

    • Thorsten Hugel
    News & Views
  • By combining fibre-based trapping and position detection with cold damping through planar electrodes, cooling of a silica nanoparticle particle motion to a few hundred phonons on a chip is achieved.

    • Bruno Melo
    • Marc T. Cuairan
    • Romain Quidant
    ArticleOpen Access
  • Nanocarrier delivery has huge potential in agriculture; however, there are significant scientific and societal barriers to overcome. In this Review, the authors explore the state of the field, what lessons can be learned from nanomedicine, and discuss what scientific and societal issues need to be addressed.

    • Gregory V. Lowry
    • Juan Pablo Giraldo
    • Jason C. White
    Review Article
  • Nanowires enable efficient genetic engineering of non-activated naive T cells, providing a technological platform for the generation of gene-modified T cells with maximal therapeutic efficacy.

    • Dragana Slavkovic-Lukic
    • Luca Gattinoni
    News & Views
  • Atomic force microscopy (AFM) is coupled with time-domain two-dimensional infrared (2DIR) spectroscopy to develop AFM-2DIR nanospectroscopy, which combines the spatial precision of AFM with the rich spectroscopic information provided by 2DIR spectroscopy. Application of this method reveals the anharmonicity of a carbonyl vibrational mode and the possible energy transfer pathways of hyperbolic phonon polaritons in isotope-rich hexagonal boron nitride.

    Research Briefing
  • Advances in nanoscale engineering bring us closer to unlocking the full potential of perovskite light-emitting diodes for future lighting and display applications.

  • A single monolayer semiconductor integrated into a plasmonic tunnel junction exhibits electroluminescence with photon energies that exceed the excitation electron potential. This phenomenon is shown to be indirectly triggered by inelastically tunnelling electrons.

    Research Briefing