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Approaches to treat inflammatory bowel disease with probiotics or artificial enzymes have advantages and limitations. Here we combine the advantages to overcome the individual limitations by modifying probiotics with artificial enzymes and demonstrate application in treating inflammatory bowel disease.

A simple descriptor called degree-of-isolation is proposed to describe the microenvironment and determine the effectiveness of active sites in single-site alloys. For a single-site alloy with a high degree-of-isolation, alternation of the active centre strongly affects the selectivity.

Moiré lattice reconstruction on mesoscopic length scales gives rise to diverse exciton signatures within emergent domains of different dimensionality.

The authors use a DNA-framework-based molecular classifier to perform biomarker panel screening and analyse six biomarkers across three-dimensional datatypes to obtain a molecular taxonomy for prostate cancer diagnosis.

The n- and p-type channel characteristics of WSe₂ are exploited to implement multiply–accumulate and activation functions simultaneously in an in-memory computing core.

In multilayer WSe₂, dipolar excitons with Coulomb-bound electron and hole pairs located in every other layer show unique valleytronic superlattice structure and electrical tunability.

High-T_c superconducting nanowire detectors can detect single photons of telecom wavelengths at a temperature of 25 K and may enable applications in quantum sensing and quantum information processing.

Superconducting single-photon detectors are critical for quantum communication, fluorescence lifetime imaging and remote sensing, but commonly operate at very low temperatures. Now, high-temperature cuprate superconducting nanowires enable single-photon detection up to 25 K.

Differential phase contrast scanning transmission electron microscopy probes the electric field distribution across a GaN-based semiconductor heterointerface.

A semirigid stamp and a standard photolithography mask-aligner enable a reliable and scalable pickup and release process for van der Waals materials integration at the wafer scale.

Multiple alternating layers of two-dimensional materials and epilayers are grown on III–N and III–V substrates in a single growth run. Then, each epilayer is harvested by mechanical exfoliation, producing multiple freestanding membranes from a single wafer.

By integrating split ferroelectric capacitors with complementary characteristics in the same memory cell, this architecture tackles the problem of conflicting memory requirements for training and inference, which has long plagued edge intelligence applications.

A flash memory device fabricated with atomically sharp van der Waals heterostructures shows a programming speed of 20–30 ns and power consumption in the nanowatt region.

Since the early 1990s, the intersection of genetics and nanomedicine has found a home in the clinic as one of the game changers of the past decade, holding great promise in fighting diseases by rapidly developing much-needed therapeutic platforms, from cancer to infectious or genetic diseases. And this revolution was just triggered by the amazing evolving world of messenger RNA and its ‘cues’.

Mechanically rigid and geometrically stable nano-scaffolds decrease intermembrane spacing at the immunological synapse, leading to the exclusion of tyrosine phosphatase CD45 protein and enhancement of T-cell signalling.

The authors developed a highly conductive and dielectric composite solid-state electrolyte by coupling BaTiO₃ and Li_0.33La_0.56TiO_3–x nanowires with a side-by-side heterojunction structure in a polyvinylidene difluoride matrix, which simultaneously promotes the dissociation of lithium salts to produce more movable Li ions and efficiently transports the generated movable Li ions.

Biodegradable polylactic acid (PLA) microplastics are shown to undergo enzymatic hydrolysis by lipases found in the human gut to generate PLA oligomers, which self-aggregate to form nanoplastic particles. The oligomers and their nanoparticles bioaccumulated in multiple organs of a mouse model and caused acute intestinal inflammation.