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Volume 2 Issue 3, March 2017

Volume 2 Issue 3

Hot rod

RodA is a glycosyltransferase found in Bacillus subtilis; bacterial extracts may be able to target the peptidoglycan polymerase pathway and serve as an antibiotic.

See Emami et al. 2, 16253 (2017)


Image: Kaveh EmamiCover Design: Samantha Whitham


  • Editorial |

    While deaths from leading infectious diseases have decreased since the millennium, the threat from potential new outbreaks means that complacency is not an option. The global health community is grossly underprepared to meet new epidemic challenges, but signs suggest that improvement is underway.

Comment & Opinion

  • Comment |

    CRISPR–Cas is an adaptive immune system found in Bacteria and Archaea that confers sequence-specific protection against invasion by foreign nucleic acids. CRISPR–Cas is also a powerful tool for microbiology education and has been an inspiring model for our students for the past three years.

    • Luc Trudel
    • Michel Frenette
    • Sylvain Moineau
  • Q&A |

    Following the launch of an initiative at the World Economic Forum to prevent future epidemics, we spoke to the scientist at the helm of this coalition, John-Arne Røttingen, who answered our questions on epidemic preparedness, moving from academia to public health policy, evidence-based decision-making, and more.

    • Nonia Pariente

News & Views

  • News & Views |

    Recent work characterizing CozE, a protein that controls the function of the class A penicillin-binding protein PBP1a, sheds new light on our understanding of the synthesis of the bacterial peptidoglycan shell.

    • Adrien Ducret
    • Christophe Grangeasse
  • News & Views |

    A newly identified phosphoinositide kinase helps to generate phosphatidylinositol 4-phosphate (PtdIns4P) on the vacuolar membrane of the intracellular pathogen Legionella pneumophila. Sequential effector protein cooperation explains the unusual enrichment of PtdIns4P on the Legionella-containing vacuole.

    • Elizabeth L. Hartland



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