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Volume 2 Issue 1, January 2017

Volume 2 Issue 1

Imprinting on infection

Previous infection with Escherichia coli epigenetically alters host epithelial cell maturation and COX-2-mediated inflammation to predispose mice for future recurrent infection.

See O'Brien et al. 2, 16196 (2016)

Image: Valerie P. O'Brien, Matthew Joens, Jaclynn Lett, James A. Fitzpatrick & Scott J. Hultgren 

Editorial

  • Editorial |

    As we enter 2017, Nature Microbiology completes its first year as a journal dedicated to publishing work of the highest quality from across the field. And what a year it has been. We take this opportunity to mark up the report card and check on our progress.

Comment & Opinion

  • Comment |

    Marine microorganisms inhabit diverse environments and interact over different spatial and temporal scales. To fully understand how these interactions shape genome structures, cellular responses, lifestyles, community ecology and biogeochemical cycles, integration of diverse approaches and data is essential.

    • Corina P. D. Brussaard
    • Kay D. Bidle
    • Catherine Legrand

News & Views

  • News & Views |

    The biologically active form of vitamin B1 is not required by Borrelia burgdorferi, the bacterium that causes Lyme disease, challenging the paradigm that this vitamin is essential for all living organisms.

    • Diana Downs
  • News & Views |

    Type VII protein secretion systems are most widely associated with virulence in bacterial pathogens. A new study reveals a type VII system-secreted nuclease toxin that specifically affects clonally unrelated strains, thus placing type VII secretion directly into the fray of microbial competition.

    • Tatyana A. Sysoeva
    • Briana M. Burton
  • News & Views |

    Bacterial infection of the bladder can lead to mucosal remodelling and increased predisposition to recurrent infection, changing the way we view host susceptibility and providing new opportunities to develop novel therapeutics.

    • Glen C. Ulett
    • Mark A. Schembri

Reviews

  • Review Article |

    The symbiosis between UCYN-A and haptophyte picoplankton plays a major role in oceanic nitrogen cycling. Though it bears some resemblance to freshwater examples, making it an interesting marine model, UCYN-A diversity means that many questions remain.

    • Jonathan P. Zehr
    • Irina N. Shilova
    • Kendra A. Turk-Kubo

Research

Amendments & Corrections

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