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Comprenhensive analysis of human antibody responses to SARS-CoV-2 variants and animal sarbecoviruses finds that Omicron escapes neutralization more readily than distantly related animal sarbecoviruses.
The closed chromosome of an Asgard archaeon, Candidatus Odinarchaeum yellowstonii LCB_4, revealed CRISPR spacers, which were used to identify archaeal viruses.
The SARS-CoV-2 Lambda variant has been prevalent in Latin America. An analysis of the neutralization capacity of antibodies elicited by CoronaVac and BNT162b2 against SARS-CoV-2 Lambda in plasma from healthcare workers and patients in Chile reveals that BNT162b2 elicits higher neutralizing antibody titres than CoronaVac.
A third vaccination with BNT162b2 against SARS-CoV-2 elicits antibody and T-cell responses in 4 out of 5 reported older adults who were previously low-/non-responders.