Genomic epidemiology of Vibrio cholerae isolates recovered between 2016 and 2019 during the Yemen cholera outbreak reveals acquisition of multidrug resistance and patterns of plasmid transmission between endemic and epidemic lineages.

Pangolin coronavirus GD has reduced replication and transmission fitness compared with SARS-CoV-2, and therapies approved for SARS-CoV-2 are effective against this virus.

Electron cryo-microscopy revealed that ribosomes from microsporidian parasites were in a hibernating state, whereby the ribosomes form inactive pairs.

The gut commensal Akkermansia muciniphila regulates food allergy symptoms in a diet-dependent manner in mice.

Genomic epidemiology of Vibrio cholerae isolates recovered between 2016 and 2019 during the Yemen cholera outbreak reveals acquisition of multidrug resistance and patterns of plasmid transmission between endemic and epidemic lineages.

Antibacterial combinations that are potent against Gram-positive bacteria are identified using an automated high-throughput screen.

Culture-independent CRISPR spacer screens enable the discovery of hundreds of viruses and mobile genetic elements infecting all known methanogenic lineages.

Pangolin coronavirus GD has reduced replication and transmission fitness compared with SARS-CoV-2, and therapies approved for SARS-CoV-2 are effective against this virus.

Electron cryo-microscopy revealed that ribosomes from microsporidian parasites were in a hibernating state, whereby the ribosomes form inactive pairs.

The gut commensal Akkermansia muciniphila regulates food allergy symptoms in a diet-dependent manner in mice.

Thumbi Ndung’u reminisces about how far we have come in our fight against HIV-1, a pandemic virus that causes AIDS, and where we still need to go.

As more PhD students and postdoctoral fellows transition to professions outside academia, training programmes must prepare scientists for these alternative careers.

Investment in a new tuberculosis vaccine is a landmark step forward, but continued efforts to advance treatments, diagnostics and biosocial issues are needed to meet targets to end the epidemic by 2035.

The global outbreak of H5N1 highly pathogenic avian influenza virus and its high toll on animal populations raise concerns about spillover into humans, but human host barriers need to be considered when estimating transmission potential.

Carl Nathan describes how learning from Mycobacterium tuberculosis, which causes tuberculosis, teaches us about the intricacies of bacteria–immune system interplay and its repercussions for non-infectious diseases, including cancer.