Linqi Wang

Cryptococcus neoformans sexual reproduction is controlled by a quorum sensing peptide

Latest Research

  • Letter |

    Live-cell imaging reveals that type IV competence pili from naturally competent Vibrio cholerae are dynamic structures that bind to exogenous DNA via their tips. Pilus retraction pulls DNA to the cell surface and across the outer membrane to initiate DNA uptake.

    • Courtney K. Ellison
    • , Triana N. Dalia
    • , Alfredo Vidal Ceballos
    • , Joseph Che-Yen Wang
    • , Nicolas Biais
    • , Yves V. Brun
    •  & Ankur B. Dalia
  • Article | | open

    Recovery of population genomes from surface ocean samples identified non-cyanobacterial diazotrophs that were widespread and abundant, including Proteobacteria and Planctomycetes, indicating their importance for nitrogen fixation in this environment.

    • Tom O. Delmont
    • , Christopher Quince
    • , Alon Shaiber
    • , Özcan C. Esen
    • , Sonny TM Lee
    • , Michael S. Rappé
    • , Sandra L. MacLellan
    • , Sebastian Lücker
    •  & A. Murat Eren
  • Letter |

    Viral protein X from HIV-2/SIV targets the HUSH (TASOR, MPP8 and periphilin) complex for proteasomal degradation through recruitment of the DCAF1 ubiquitin ligase adaptor, enabling reactivation of latent proviruses.

    • Ghina Chougui
    • , Soundasse Munir-Matloob
    • , Roy Matkovic
    • , Michaël M Martin
    • , Marina Morel
    • , Hichem Lahouassa
    • , Marjorie Leduc
    • , Bertha Cecilia Ramirez
    • , Lucie Etienne
    •  & Florence Margottin-Goguet
  • Review Article |

    This Review Article discusses the role of bacteriophages in the marine environment, including interactions with their bacterial hosts and their impact on biogeochemical cycling, and a hypothesis to explain successional host–phage dynamics in marine systems.

    • Mya Breitbart
    • , Chelsea Bonnain
    • , Kema Malki
    •  & Natalie A. Sawaya
  • Article |

    A calcium–calmodulin signalling pathway is identified as a master regulator of light chain 3 (LC3)-associated phagocytosis. Aspergillus melanin sequesters Ca2+ inside the phagosome, inhibiting this pathway, which is important in human aspergillosis.

    • Irene Kyrmizi
    • , Helena Ferreira
    • , Agostinho Carvalho
    • , Julio Alberto Landero Figueroa
    • , Pavlos Zarmpas
    • , Cristina Cunha
    • , Tonia Akoumianaki
    • , Kostas Stylianou
    • , George S. Deepe Jr
    • , George Samonis
    • , João F. Lacerda
    • , António Campos Jr
    • , Dimitrios P. Kontoyiannis
    • , Nikolaos Mihalopoulos
    • , Kyung J. Kwon-Chung
    • , Jamel El-Benna
    • , Isabel Valsecchi
    • , Anne Beauvais
    • , Axel A. Brakhage
    • , Nuno M. Neves
    • , Jean-Paul Latge
    •  & Georgios Chamilos

News & Comment

  • News & Views |

    Antibiotic resistance against β-lactams is of paramount therapeutic importance. Although such resistance is known to involve degradation by hydrolysis, the molecular details of what happens next remain unclear. A new study reveals how soil microbes perform β-lactam catabolism and how this process can support bacterial growth.

    • Christopher J. Schofield
  • News & Views |

    The discovery and characterization of a phylum-level archaeal lineage in iron-rich hot springs—the Marsarchaeota—expands the phylogenetic depth and physiological diversity of aerobic archaea.

    • Andreas Teske
  • News & Views |

    Comparative genomics of all known Laverania species that infect African great apes reveals interspecies gene transfer and convergent evolution, and identifies features of Plasmodium falciparum, the only human-infective species within this subgenus, that may have led to its speciation and spread globally.

    • Jane M. Carlton
  • Editorial |

    Although the spotlight on CRISPR–Cas systems has shone on their immense potential as genome-editing tools, the field’s origins are rooted in the microbiology of phage–bacterium interactions. Furthering our understanding of these processes can uncover more systems and generate new reagents with revolutionary properties.

  • News & Views |

    Genetic integration of a humanized chemotaxis receptor unexpectedly reveals that a widely expressed immune protein is targeted by Staphylococcus aureus Panton–Valentine leukocidin in a novel way, changing our fundamental understanding of toxin–receptor biology and host–pathogen interaction.

    • Brandon Lee
    •  & Juliane Bubeck Wardenburg
  • News & Views |

    The small intestine microbiome has been revealed to play a critical role in nutritional signal transduction that enables the host to adapt its fat digestion and absorption capacities, suggesting that this microbial community may serve as a target to improve conditions of over- and undernutrition.

    • Michiel Kleerebezem

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