Volume 4 Issue 9, September 2007

Artistic interpretation by Erin Boyle of a Katushka fluorescent protein expression in a Xenopus laevis frog bearing the Katushka transgene under the control of a cardiac actin promoter. Protein structure representation is derived from the related protein egFP611. Frog image provided by Konstantin Lukyanov and Andrey Zaraisky.

Editorial

A 'rough guide' to publication

Submitting or resubmitting a manuscript—some important steps and decisions along the way.

Editorial 01 Sept 2007

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Correspondence

An experimental correction for arginine-to-proline conversion artifacts in SILAC-based quantitative proteomics

Dennis Van Hoof
Martijn W H Pinkse
Jeroen Krijgsveld
Correspondence 01 Sept 2007
New lasers for flow cytometry: filling the gaps

Veena Kapoor
Fedor V Subach
William G Telford
Correspondence 01 Sept 2007
SNPs matter: impact on detection of differential expression

Nicole A R Walter
Shannon K McWeeney
Kari J Buck
Correspondence 01 Sept 2007

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Research Highlights

Incredible shrinking optics

Daniel Evanko
Research Highlights 01 Sept 2007
Switching genes off—all the way

Nicole Rusk
Research Highlights 01 Sept 2007
Putting a trace on metabolites

Allison Doerr
Research Highlights 01 Sept 2007
News in brief

Research Highlights 01 Sept 2007
Viral checkmate

Natalie de Souza
Research Highlights 01 Sept 2007
Amplifying the ancients

Natalie de Souza
Research Highlights 01 Sept 2007
Transcription factors come to call

Nicole Rusk
Research Highlights 01 Sept 2007

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News & Views

Channeling the worm: microfluidic devices for nematode neurobiology

Precisely scaled microfluidics channels for optical recordings of neuronal activity in live and behaving organisms.

Shawn Lockery
News & Views 01 Sept 2007
Hunting for ion channel modulators with herpes simplex virus

An innovative use of HSV-1 vectors lays the foundation for a novel genetic screen for modulators of ligand-gated ion channels.

Daniel N Cortright
Marianne E Buck
James E Krause
News & Views 01 Sept 2007
Soaking up small RNAs

MicroRNAs are not amenable to classical RNAi-based knockdown strategies, but genetic 'sponges' that compete microRNAs away from their natural targets create a microRNA 'knockdown'.

Scott M Hammond
News & Views 01 Sept 2007

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Perspective

Solution NMR of supramolecular complexes: providing new insights into function

Remco Sprangers
Algirdas Velyvis
Lewis E Kay
Perspective 01 Sept 2007

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Brief Communication

High-throughput cloning and expression in recalcitrant bacteria

Eric R Geertsma
Bert Poolman
Brief Communication 22 Jul 2007
Higher-energy C-trap dissociation for peptide modification analysis

Jesper V Olsen
Boris Macek
Matthias Mann
Brief Communication 26 Aug 2007
Highly efficient somatic-mutation identification using Escherichia coli mismatch-repair detection

Brock A Peters
Zhengyan Kan
Somasekar Seshagiri
Brief Communication 19 Aug 2007
Tomographic phase microscopy

Wonshik Choi
Christopher Fang-Yen
Michael S Feld
Brief Communication 12 Aug 2007

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Article

MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells

Margaret S Ebert
Joel R Neilson
Phillip A Sharp
Article 12 Aug 2007
Microfluidics for in vivo imaging of neuronal and behavioral activity in Caenorhabditis elegans

Nikos Chronis
Manuel Zimmer
Cornelia I Bargmann
Article 19 Aug 2007
An HSV vector system for selection of ligand-gated ion channel modulators

Rahul Srinivasan
Shaohua Huang
Joseph C Glorioso
Article 05 Aug 2007
Bright far-red fluorescent protein for whole-body imaging

Dmitry Shcherbo
Ekaterina M Merzlyak
Dmitriy M Chudakov
Article 26 Aug 2007
Genome-wide prediction of matrix attachment regions that increase gene expression in mammalian cells

Pierre-Alain Girod
Duc-Quang Nguyen
Nicolas Mermod
Article 05 Aug 2007

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Technology Feature

Keeping tabs on fluorescent tags

Fluorescence-based reagents are quickly evolving to keep pace with the demands of many research disciplines that have grown to depend on them. Caitlin Smith takes a look at recent developments.

Caitlin Smith
Technology Feature 01 Sept 2007

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Erratum

Erratum: Eukaryotic ribosome display with in situ DNA recovery

Mingyue He
Michael J Taussig
Erratum 01 Sept 2007

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Advertising Feature: Application Note

HTRF® KinEASE™ TK: a new solution for tyrosine kinase screening

Jean-Luc Tardieu
Advertising Feature: Application Note 01 Sept 2007
Securing accuracy and precision when pipetting hot and cold liquids with Microman®

Frédéric Millet
Thierry Barthlen
Advertising Feature: Application Note 01 Sept 2007

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Volume 4 Issue 9, September 2007

Editorial

Correspondence

Research Highlights

News & Views

Perspective

Brief Communication

Article

Technology Feature

Erratum

Advertising Feature: Application Note

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