News & Comment

Filter By:

  • Array tomography opens the door to the large-scale exploration of molecular diversity of individual brain synapses.

    • Erika Pastrana
    Research Highlights
  • RNA molecules can both induce pluripotency and direct differentiation.

    • Monya Baker
    Research Highlights
  • A predictive model of intercellular metabolic interactions in the human brain is reported.

    • Natalie de Souza
    Research Highlights
  • Three groups achieve room-temperature, single-molecule detection of nonfluorescent, photon-absorbing compounds.

    • Michael Eisenstein
    Research Highlights
  • A team of researchers applied a 'discovery single-particle profiling' experimental strategy to visualize the assembly of the ribosome via time-resolved electron microscopy.

    • Allison Doerr
    Research Highlights
  • The low cost of short-read sequencing has motivated the development of de novo assemblies from only short-read data; impressively, assemblies for large mammalian genomes are now available. However, this is still a developing field, and these de novo assemblies have many artifacts, as do all de novo assemblies.

    • Ewan Birney
    Commentary
  • Small conditional RNAs prove their mettle in multiplexed mRNA imaging and show promise as potential cancer therapeutics.

    • Nicole Rusk
    Research Highlights
  • Fluorescent proteins can be located in electron micrographs.

    • Monya Baker
    • Erik Jorgensen
    This Month
  • Advances in microfluidics and imaging, combined with some high-profile studies, are increasing interest in whole-organism screening.

    • Monya Baker
    Technology Feature
  • The payoffs for efficient cargo delivery into living cells make the development of better methods worthwhile.

    • Nicole Rusk
    Method to Watch
  • Targeted analysis of proteins on a broad scale with mass spectrometry is becoming a reality.

    • Allison Doerr
    Method to Watch
  • The use of adaptive optics to correct light distortions promises to greatly improve the imaging quality of thick biological tissues.

    • Erika Pastrana
    Method to Watch
  • In 2011, we will see the arrival of new and improved sequencing technologies.

    • Nicole Rusk
    Method to Watch
  • Genome-engineering tools with improved design and efficiency will become widely used.

    • Natalie de Souza
    Method to Watch