iPS cell technology makes patient- and disease-specific human cells widely available. While technical challenges still remain, the use of these tools will greatly expand our understanding of human disease.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Inborn errors of metabolism: Lessons from iPSC models
Reviews in Endocrine and Metabolic Disorders Open Access 09 July 2021
-
Lysosomal and network alterations in human mucopolysaccharidosis type VII iPSC-derived neurons
Scientific Reports Open Access 09 November 2018
-
Increased nicotine response in iPSC-derived human neurons carrying the CHRNA5 N398 allele
Scientific Reports Open Access 04 October 2016
Access options
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Wilmut, I., Schnieke, A.E., McWhir, J., Kind, A.J. & Campbell, K.H. Nature 385, 810–813 (1997).
Wakayama, T. et al. Science 292, 740–743 (2001).
Munsie, M.J. et al. Curr. Biol. 10, 989–992 (2000).
Verlinsky, Y. et al. Reprod. Biomed. Online 10, 105–110 (2005).
Eiges, R. et al. Cell Stem Cell 1, 568–577 (2007).
Mateizel, I. et al. Hum. Reprod. 21, 503–511 (2006).
Takahashi, K. & Yamanaka, S. Cell 126, 663–676 (2006).
Okita, K., Ichisaka, T. & Yamanaka, S. Nature 448, 313–317 (2007).
Wernig, M. et al. Nature 448, 318–324 (2007).
Zhao, X.Y. et al. Nature 461, 86–90 (2009).
Kang, L., Wang, J., Zhang, Y., Kou, Z. & Gao, S. Cell Stem Cell 5, 135–138 (2009).
Takahashi, K. et al. Cell 131, 861–872 (2007).
Yu, J. et al. Science 318, 1917–1920 (2007).
Park, I.H. et al. Cell 134, 877–886 (2008).
Dimos, J.T. et al. Science 321, 1218–1221 (2008).
Soldner, F. et al. Cell 136, 964–977 (2009).
Ebert, A.D. et al. Nature 457, 277–280 (2009).
Lee, G. et al. Nature 461, 402–406 (2009).
Axelrod, F.B. Expert Opin. Pharmacother. 6, 561–567 (2005).
Ye, Z. et al. Blood published online, doi: 10.1182/blood-2009-04-217406 (1 October 2009)
Placantonakis, D.G. et al. Stem Cells 27, 521–532 (2009).
Hockemeyer, D. et al. Nat. Biotechnol. 27, 851–857 (2009).
Di Giorgio, F.P., Carrasco, M.A., Siao, M.C., Maniatis, T. & Eggan, K. Nat. Neurosci. 10, 608–614 (2007).
Nagai, M. et al. Nat. Neurosci. 10, 615–622 (2007).
Raya, A. et al. Nature 460, 53–59 (2009).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Lee, G., Studer, L. Induced pluripotent stem cell technology for the study of human disease. Nat Methods 7, 25–27 (2010). https://doi.org/10.1038/nmeth.f.283
Published:
Issue Date:
DOI: https://doi.org/10.1038/nmeth.f.283
This article is cited by
-
Approaches to characterize the transcriptional trajectory of human myogenesis
Cellular and Molecular Life Sciences (2021)
-
Inborn errors of metabolism: Lessons from iPSC models
Reviews in Endocrine and Metabolic Disorders (2021)
-
Lysosomal and network alterations in human mucopolysaccharidosis type VII iPSC-derived neurons
Scientific Reports (2018)
-
Increased nicotine response in iPSC-derived human neurons carrying the CHRNA5 N398 allele
Scientific Reports (2016)
-
Trend of telomerase activity change during human iPSC self-renewal and differentiation revealed by a quartz crystal microbalance based assay
Scientific Reports (2014)
