• Collection |

    From the generation of embryo-like structures to the establishment of cell-based approaches to model or treat disease, the field of stem cell and developmental biology has impressively progressed during the past few months.

    Image: Jacob Hanna and Maayan Visuals – Oldak B. et al. Complete human day 14 post-implantation embryo models from naive ES cells. Nature 622, 562–573 (2023).
  • Collection |

    Detailed method reporting is essential for research reproducibility and trust in published results.

    Image: Sam Whitham
  • Focus |

    Methods for modeling development is our Method of the Year 2023, for the remarkable insights that recent methodological advances have enabled in our understanding of the molecular mechanisms of human embryogenesis.

    Image: Berna Sozen, Zernicka-Goetz Lab
  • Collection |

    This Collection welcomes primary research articles describing advances in computational and statistical methodology for ecology and evolution.

    Image: [M] troyanphoto /
    Open for submissions
  • Collection |

    The 2023 Nobel Prize in chemistry has been awarded to Moungi G. Bawendi, Louis E. Brus and Alexei I. Ekimov for the discovery and synthesis of quantum dots.

    Image: Springer Nature/The Nobel Foundation/Imagesource
  • Collection |

    Inaugurated in 2018, the Human BioMolecular Atlas Program (HuBMAP) endeavours to construct comprehensive spatial maps that feature a range of biomolecules such as RNA, proteins, and metabolites in human organs at single-cell resolution.

    Image: Heidi Schlehlein
  • Focus |

    Ideas from computer vision have transformed the way image analysis is performed, with ripple effects across microscopy and biological discovery.

    Image: Loic Royer and Merlin Lange, Chan Zuckerberg Biohub
  • Collection |

    Stem cell models of development, regeneration, and disease are quickly advancing. New technologies and concepts are continuously combined with existing knowledge to create more realistic systems to improve our understanding of these intricate processes. In this collection, we highlight papers published in 2022-2023 across Nature Portfolio journals on topics including embryonic development and stem cells, reproductive biology, synthetic tissues and embryo models, clinical and translational research and tissue stem cells.

    Image: Jean-Baptiste Sibarita, Virgile Viasnoff, and Anne Beghin
  • Special |

    The human reference genome is fundamental to basic, translational and clinical research.

    Image: Darryl Leja/NHGRI; Sequence map: Adam Novak/UCSC
  • Focus |

    The emerging field of single-cell proteomics is undergoing a phase of rapid technology development, including advances in mass spectrometry-based methods and single-molecule protein sequencing approaches.

    Image: Luis Schachner / Dream by WOMBO / DALL-E by OpenAI
  • Collection |

    Selected, recent articles from across the Nature Portfolio that document the recent progress in understanding the biology of EV-mediated cell–cell communication and advances in clinical translation of EVs.

    Image: Vicky Summersby