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It's been a long wait for nanopore sequencing technology. Over 1,000 labs are testing the first commercial device and publishing results. Researchers tell Nature Methods about their experiences putting these early instruments through their paces. And more technology is in the works.
Large-scale phenotyping is generating much data that geneticists can harness. Amid the excitement about the possibilities, there are some points of caution.
Blinking and photobleaching of fluorophores cause challenges in a whole range of imaging experiments. Here are some ways researchers are approaching fluorophore photostability.