Research Highlights

A bioengineering and machine learning-guided approach models human axial development and somitogenesis in vitro.

Two research groups independently develop tools to record the history of cellular dynamics.

A new twist on expansion microscopy called Magnify uses a mechanically sturdy gel to simultaneously anchor and expand diverse biological samples for super-resolution imaging.

Spatially resolved and single-cell transcriptomics provide insights into tumor heterogeneity and tumor–microbiome interactions.

An approach combining in situ tagmentation and transcription with MERFISH enables spatial profiling of the epigenome in tissues with single-cell resolution.

Researchers use electric fields to transfer RNA from a tissue sample onto a surface for subsequent fluorescence in situ hybridization-based profiling of transcriptomes at the single-cell level.