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Beyond protein destruction: a new real-time assay to measure dynamic changes in ubiquitination promises to highlight the many other roles of this critical protein modification.
With the sequencing of the human genome, millions of single-nucleotide polymorphisms, or SNPs, have been discovered and can be used as markers to identify genes contributing to common human diseases. Two large sets of SNPs have now been organized in panels for high-throughput genotyping.
Rapid and accurate identification of protein phosphorylation sites is achieved by a peptide library screen combining the advantages of chemistry in solution and analysis on solid support.
A sequence-independent procedure for rapid identification of plant centromeric DNA provides a new tool for genome assembly and genomic evolution studies.
