Editorials

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  • As 2022 draws to a close, we highlight some of our favorite papers that we published this year in Nature Methods.

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  • This month we continue our yearly celebration of the beauty of imaging.

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  • Research interest in noncoding RNAs and their biological implications in a variety of cellular contexts has been growing. In this issue, we present a series of pieces discussing recent method advances and future directions for deciphering the regulatory roles of noncoding RNAs.

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  • As pandemic restrictions ease and we at Nature Methods begin to travel again, we muse about the highs and lows of in-person and virtual meetings and imagine the future of scientific conferences.

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  • In this issue, we are delighted to launch a new regular feature: the Creature Column.

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  • Nature Methods is pleased to publish several papers presenting methods developed by members of the Telomere-to-Telomere (T2T) Consortium, which facilitated the generation and analysis of the first complete human genome.

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  • It’s been a busy start to 2022 in the editorial offices of Nature Methods. We summarize several developments here: new content types, editorial initiatives, travel and outreach, and recent Focus issues.

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  • The COVID-19 pandemic has highlighted the importance of methodological advancements in basic biological research. We believe that method development will continue to propel both fundamental and applied studies on SARS-CoV-2 and other pathogens.

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  • Highly multiplexed tissue imaging continues to show its power for biomedical discovery. In this issue, we publish tools and guidance for implementing this class of methods and reporting subsequent results.

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  • Nature Methods is introducing a new article format: Registered Reports. We encourage all authors interested in submitting comparative analyses of the performance of established, related tools or methods to familiarize themselves with this alternative approach to peer review.

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  • Guidelines for improving reporting and reproduciblity in microscopy take center stage in this month’s Focus issue.

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  • This month, we celebrate the value and beauty of images of biological processes captured by microscopes.

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  • Community-driven initiatives are proposing standards to improve the reporting and reproducibility of machine learning in biology. We support these developments, some of which are described in this month’s special issue.

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  • Constructing a fair and accurate author list can be one of the most fraught aspects of manuscript publication. We provide some advice and resources for authors at all career levels.

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  • Professional editing can be a rewarding career. Here we discuss what the job entails, highs and lows, how to prepare for this career, the interview process and more.

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  • Computation goes hand in hand with contemporary biological studies. We describe a few trends in computational science that are helping drive new biological knowledge.

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  • Researchers, funders, database managers and journals all have a role to play in accounting for diversity and prioritizing inclusion at the basic science level.

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  • The Protein Data Bank (PDB) is the primary data resource for structural biology. On its 50th anniversary, we celebrate the future of this ever-growing field.

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