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Miniature, transparent Danionella fishes, which are among the smallest living adult vertebrates, allow investigation of general principles of brain-wide neural circuits and evolutionary and developmental mechanisms for neurobehavioral innovations.
SCUBA-D is a denoising diffusion probabilistic model that can perform a variety of protein backbone design tasks, including generation of backbones from random noise, from user-sketched designs, and backbones to scaffold predefined motifs that can bind small molecules or other proteins.