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  • Confetti conceptually illustrates the broad diversity of noncoding RNAs

    Research interest is growing in profiling noncoding RNAs and understanding their biological functions in health and disease contexts. The articles featured in this collection highlight recent method developments and key resources that enable researchers to further explore the noncoding RNA field.

  • Virus particle

    The COVID-19 pandemic has been marked by speedy scientific progress boosted by decades of methods development for basic biological research. Here, we highlight some of the key advancements that have facilitated the scientific response to SARS-CoV-2.

  • Complete human genome

    The Telomere-to-Telomere (T2T) Consortium has generated the first complete human genome. Some of the methods and results from the consortium are presented here along with expert commentary on this milestone.

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Method of the Year 2021: Protein structure prediction

Protein structure prediction is our Method of the Year 2021, for the remarkable levels of accuracy achieved by deep learning-based methods in predicting the 3D structures of proteins and protein complexes, essentially solving this long-standing challenge.
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