• colorful fluorescent zebrafish embryos

    Ideas from computer vision have transformed the way image analysis is performed, with ripple effects across microscopy and biological discovery. This Focus issue brings together expert opinions on exciting directions for bioimage analysis over the next 5-20 years.

  • a plant and a keyboard

    We are looking to expand our journal scope to include more ecology papers, particularly those describing methods for quantitative analysis of ecological and evolutionary data. Published papers will be added to this Collection.

    Open for submissions

Nature Methods is a Transformative Journal; authors can publish using the traditional publishing route OR via immediate gold Open Access.

Our Open Access option complies with funder and institutional requirements.


  • Developments in nanopore-based peptide detection and sequencing show promise of a breakthrough.

    • Arunima Singh
    Method to Watch
  • Spatially resolved multimodal omics offers a collective way to capture molecular information in complex tissues.

    • Lei Tang
    Method to Watch
  • High-resolution connectomics of the human brain is the next frontier in neuroscience.

    • Nina Vogt
    Method to Watch
  • New twists on established methods and multimodal imaging are poised to bridge gaps between cellular and organismal imaging.

    • Rita Strack
    Method to Watch

Method of the Year 2021: Protein structure prediction

Protein structure prediction is our Method of the Year 2021, for the remarkable levels of accuracy achieved by deep learning-based methods in predicting the 3D structures of proteins and protein complexes, essentially solving this long-standing challenge.


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