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CryoREAD provides fully automated DNA–RNA structure modeling for cryo-EM maps
CryoREAD automatically builds DNA–RNA atomic structure from cryo-EM maps. Backbone accuracy is typically >85% and the method is applicable for maps with RNA-only, DNA-only and DNA–RNA–protein complex structures. CryoREAD uses deep learning to identify structure information and subsequently construct the 3D structure of nucleic acids.
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Method of the Year 2021: Protein structure prediction
Protein structure prediction is our Method of the Year 2021, for the remarkable levels of accuracy achieved by deep learning-based methods in predicting the 3D structures of proteins and protein complexes, essentially solving this long-standing challenge.