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Volume 18 Issue 8, August 2019

Suppressing implant fibrosis

Foreign body response can result in failure of biomaterials in vivo. Solvent-free crystals containing anti-fibrotic drugs now show the potential for long-term inhibition of fibrosis on a number of implantable devices in rodents and non-human primates.

See Farah et al. and Bank News & Views.

IMAGE: Joshua Doloff*, Shady Farah* and Felice Frankel, Massachusetts Institute of Technology (*equally contributed). COVER DESIGN: David Shand.

Editorial

  • We are launching a new column to talk about science with our readers from a broader perspective. Our first topic is mental health in academia.

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News & Views

  • Quantitative atomic-scale images of electric potentials at surfaces have now been obtained with a non-contact atomic force microscope by functionalizing the tip as a quantum dot sensor.

    • Mats Persson
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  • Granular aluminium — a superconductor with high kinetic inductance — has been used to create a superinductor for a fluxonium superconducting qubit.

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    • William D. Oliver
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  • Thousands of electron diffraction patterns, collected stepwise by scanning transmission electron microscopy, are synchronized and mined to provide unprecedented maps of the nanostructure of ordered domains in organic electronics films.

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    • Yaron Kauffmann
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  • Highly stable and active Pt–Sn sub-nanometre clusters are located in sinusoidal zeolite channels, leading to improved and more stable propane dehydrogenation catalysts.

    • Bert M. Weckhuysen
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  • With their ability to give rise to many different cell types, stem cells have long been a target of scientists who seek to achieve control over their differentiation. New evidence suggests that stem cells influence their own fates through protein deposition and physical remodelling of their microenvironment.

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  • Crystallized anti-inflammatory drugs have been shown to inhibit fibrosis on the surface of a number of devices over a long-term period following implantation in rodents and non-human primates.

    • Ruud A. Bank
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Review Articles

  • This Review discusses recent developments in the area of non-Hermitian physics, and more specifically the special case of non-Hermitian optical systems with parity–time symmetry.

    • Ş. K. Özdemir
    • S. Rotter
    • L. Yang
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  • The droplet epitaxy technique has emerged as an alternative to the most commonly used Stranski–Krastanov for fabricating semiconductor nanostructures. This Review discusses the important aspects of droplet epitaxy quantum dots, from the growth mechanism to device application.

    • Massimo Gurioli
    • Zhiming Wang
    • Stefano Sanguinetti
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  • Donata Iandolo and Gonçalo Silva on the need for an open discussion on mental health in academia.

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    • Gonçalo Silva
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