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Stem cell isolation

Differential stickiness

Nature Materials volume 12, pages 474–476 (2013)Cite this article

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Technologies to isolate colonies of human pluripotent stem cells from other cell types in a high-throughput manner are lacking. A microfluidic-based approach that exploits differences in the adhesion strength between these cells and a substrate may soon fill the gap.

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Figure 1: The strength of adhesion between stem cells and a substrate changes with hiPSC reprogramming and differentiation10.
Figure 2: Adhesion strength-based isolation of stem cells10.

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Authors and Affiliations

  1. Oscar J. Abilez and Joseph C. Wu are at the Department of Medicine, the Institute for Stem Cell Biology and Regenerative Medicine, and the Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, California 94305, USA,

    Oscar J. Abilez & Joseph C. Wu

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  1. Oscar J. Abilez
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  2. Joseph C. Wu
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Correspondence to Oscar J. Abilez or Joseph C. Wu.

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Abilez, O., Wu, J. Differential stickiness. Nature Mater 12, 474–476 (2013). https://doi.org/10.1038/nmat3664

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