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  • M. I. Eremets, V. S. Minkov, A. P. Drozdov and P. P. Kong discuss the substantial progress made in discovering and developing near-room-temperature superconductivity in hydrogen-rich materials. They focus on achieving reproducibility under the challenging experimental conditions of megabar pressures.

    • M. I. Eremets
    • V. S. Minkov
    • P. P. Kong
  • Peng Wu, Tianyi Zhang, Jiadi Zhu, Tomás Palacios and Jing Kong discuss the reproducibility issues in the synthesis and device fabrication of two-dimensional transition metal dichalcogenides that need to be addressed to enable the lab-to-fab transition.

    • Peng Wu
    • Tianyi Zhang
    • Jing Kong
  • Marc Legros, Frédéric Mompiou and Daniel Caillard discuss the different aspects that influence the reproducibility and reliability of characterizations performed using in situ mechanical tests in transmission electron microscopes.

    • Marc Legros
    • Frédéric Mompiou
    • Daniel Caillard
  • Kinetic trapping in supramolecular gels leads to varied morphologies and macroscopic properties. Emily R. Draper and Dave J. Adams discuss subtle experimental effects that can lead to reproducibility issues in these systems.

    • Emily R. Draper
    • Dave J. Adams
  • The materials modelling community is emerging as a champion for reproducible and reusable science. Aron Walsh discusses how FAIR databases, collaborative codes and transparent workflows are advancing this movement.

    • Aron Walsh
  • Tae Hoon Lee and Zachary P. Smith argue that some of the most exciting materials that could be used for gas separations are metastable or crystalline, with properties that are altered by sample preparation and testing, but there are no widely accepted standards.

    • Tae Hoon Lee
    • Zachary P. Smith
  • Frustrated by reproducibility in electrical measurements on ferroelectric films, Lane Martin, Jon-Paul Maria and Darrell Schlom discuss tactics to reliably synthesize ‘good’ ferroelectric samples, especially in the search for superior materials and device heterostructures.

    • Lane W. Martin
    • Jon-Paul Maria
    • Darrell G. Schlom
  • Joseph Heremans and Joshua Martin discuss the reproducibility of thermoelectric measurements and conclude that the uncertainty on the figure of merit zT is of the order of 15–20%.

    • Joseph P. Heremans
    • Joshua Martin
  • Camille M. Le Gall, Jorieke Weiden, Loek J. Eggermont and Carl G. Figdor provide an overview of immunotherapeutics for cancer treatment that harness dendritic cells, their challenges in clinical use, and approaches employed to enhance their recruitment and activation to promote effective anti-tumour immunity.

    • Camille M. Le Gall
    • Jorieke Weiden
    • Carl G. Figdor
  • Darrell Irvine provides an overview of the recent advances in materials science that have enabled the use of innovative natural and synthetic compounds in vaccine development capable of regulating the potency and safety of new vaccines progressing towards the clinic.

    • Darrell Irvine
  • Tumour heterogeneity and off-target toxicity are current challenges of cancer immunotherapy. Karine Dzhandzhugazyan, Per Guldberg and Alexei Kirkin discuss how epigenetic induction of tumour antigens in antigen-presenting cells may form the basis for multi-target therapies.

    • Karine N. Dzhandzhugazyan
    • Per Guldberg
    • Alexei F. Kirkin
  • Kiyoshi Miyata and X.-Y. Zhu analyse the ferroelectric-like dielectric response of lead halide perovskites in the terahertz region and discuss the potential role of polar nanodomains in accounting for the defect tolerance and low recombination rates of these materials.

    • Kiyoshi Miyata
    • X.-Y. Zhu
  • Charge carriers in metal halide perovskites seem to be only marginally affected by defect-related trap states. Filippo De Angelis and Annamaria Petrozza suggest that the key to this behaviour lies in the redox chemistry of halide defects.

    • Filippo De Angelis
    • Annamaria Petrozza
  • Claudine Katan, Aditya D. Mohite and Jacky Even discuss the possible impact of various entropy contributions (stochastic structural fluctuations, anharmonicity and lattice softness) on the optoelectronic properties of halide perovskite materials and devices.

    • Claudine Katan
    • Aditya D. Mohite
    • Jacky Even
  • Heavy atoms and crystal or inversion symmetry breaking may promote Rashba effects in halide perovskites. Sam Stranks and Paulina Plochocka propose experiments to assess the existence of these effects and their implications on the photophysics of perovskites.

    • Samuel D. Stranks
    • Paulina Plochocka
  • Paulo J. M. Monteiro, Sabbie A. Miller and Arpad Horvath provide an overview of the challenges and accomplishments in reducing the environmental burden of concrete production.

    • Paulo J. M. Monteiro
    • Sabbie A. Miller
    • Arpad Horvath
  • Xiuyan Li and K. Lu discuss a strategy, alternative to alloying, to tailor the mechanical properties of metals. By engineering defects, metals with bespoke performance might be obtained while reducing the materials' compositional complexity.

    • Xiuyan Li
    • K. Lu