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Volume 27 Issue 2, February 2021

Volume 27 Issue 2

Neuromodulation for compulsive behavior

Grover and colleagues report that non-invasive modulation of high-frequency brain rhythms improves obsessive–compulsive behaviors. Using personalized high-definition transcranial alternating-current stimulation (HD-tACS), the team modulated brain rhythms in the reward-processing circuitry to reduce obsessive–compulsive symptoms. The cover depicts the neuromodulation electrodes placed on the scalp of the study participants, and represents the consequent improvements in mental health. The cover exemplifies the dawn of non-invasive neuromodulation in experimental psychiatric medicine.

See Grover and colleagues

Image credit: John Anh Nguyen. Cover design: Marina Spence.

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