Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Volume 13 Issue 4, April 2007

The germinal matrix of premature infants, densely packed with neural precursor cells and blood vessels, is selectively vulnerable to hemorrhage. In this issue, Ballabh et al. show that antiangiogenic therapy can reduce the incidence and severity of germinal matrix hemorrhage. Germinal matrix of a 24-week-old premature infant was stained to show blood vessels (laminin, white), radial glia (VEGF, red; GFAP, green) and nuclei (blue). Image courtesy of Xiaoning Han and Takahiro Takano.

Volume 13 Issue 4

Subscribe

Editorial

  • Large-scale sequencing projects to identify mutations related to cancer and psychiatric disorders will generate a lot of data. But the usefulness of these results will be limited unless we have good models to test their contribution to disease.

    Editorial

    Advertisement

Top of page ⤴

News

Top of page ⤴

Correspondence

Top of page ⤴

Book Review

Top of page ⤴

News & Views

  • Platelets act as intermediaries in the pathogenesis of sepsis—sensing bacteria and signaling neutrophils to release fibrous traps that remove bacteria from the bloodstream. This response may also contribute to tissue injury (pages 463–469).

    • Constantin Urban
    • Arturo Zychlinsky
    News & Views

  • Activation-induced cytidine deaminase (AID), which mediates antibody diversification, is now implicated as an inducer of p53 mutagenesis in cancer cells (pages 470–476).

    • Shigeo Takaishi
    • Timothy C Wang
    News & Views

  • Adenosine helps maintain proper fluid levels in the lung alveoli. The findings have implications for treatment of fluid buildup in the lung.

    • James L Kreindler
    • Steven D Shapiro
    News & Views

  • Chemokines in the brain recruit immune cells from the blood or from within the brain. Disrupting this line of communication exacerbates disease in mouse models of Alzheimer disease (pages 432–438).

    • Markus Britschgi
    • Tony Wyss-Coray
    News & Views

  • Findings from a mouse model of multiple sclerosis suggest that regulatory T cells alone cannot outduel pathogenic T cells in the central nervous system. The observations may have implications for experimental approaches designed to dampen autoimmune diseases by infusion of regulatory T cells (pages 423–431).

    • Thomas Prod'homme
    • Martin S Weber
    • Scott S Zamvil
    News & Views

  • 'Impulsivity' occurs frequently in people with addiction and other common disorders such as attention deficit hyperactivity disorder (ADHD). Experiments in rats suggest that reduced dopamine receptor availability in the brain's ventral striatum may underlie links between impulsivity and addiction.

    • George Uhl
    News & Views
Top of page ⤴

Research Highlights

Top of page ⤴

Brief Communication

Top of page ⤴

Article

Top of page ⤴

Letter

Top of page ⤴

Technical Report

Top of page ⤴

Corrigendum

Top of page ⤴

Addendum

Top of page ⤴

Search

Advanced search

Quick links