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Two biotechnology companies — and a host of other companies and research institutions — are awaiting a federal ruling on antisense technology patent rights.
The prevailing view is that a physician can simultaneously husband economic resources to control health care costs and fulfill a doctor's traditional responsibility to put the patient first. I disagree.
Antisense oligonucleotides can have dramatic effects, but a recent paper suggests that the mechanism isn't always based on nucleotide sequence interactions.
Viral resistance is a major problem with current AIDS drugs. The feline immunodeficiency virus model may provide a way to test new drugs and strategies before human trials.
Recent work suggests that the molecular basis for one form of limb-girdle muscular dystrophy is neither a single gene nor many genes: Enter the digenic model.
Dietary caloric restriction is the only intervention conclusively shown to slow ageing, delay the onset of age-related diseases, maintain function and extend both median and maximal life span in mammals.
The existence of a placental clock controlling the term of pregnancy has long been hypothesized. Now scientists may have uncovered what makes it tick (pages 460–463).
