Identification of drug targets in M. tuberculosis is a challenge for bench science. High-throughput mutagenesis with transposons together with microarray-based genome and transcriptome profiling has begun to meet this challenge.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Gandhi, N.R. et al. Lancet 368, 1575–1580 (2006).
Sassetti, C.M., Boyd, D.H. & Rubin, E.J. Mol. Microbiol. 48, 77–84 (2003).
Cole, S.T. et al. Nature 393, 537–544 (1998).
Sassetti, C.M. & Rubin, E.J. Proc. Natl. Acad. Sci. USA 100, 12989–12994 (2003).
Rengarajan, J., Bloom, B.R. & Rubin, E.J. Proc. Natl. Acad. Sci. USA 102, 8327–8332 (2005).
Warner, D.F. & Mizrahi, V. Nat. Med. 13, 282–284 (2007).
Lamichhane, G., Tyagi, S. & Bishai, W.R. Infect. Immun. 73, 2533–2540 (2005).
Jain, S.K. et al. J. Infect. Dis. (in the press).
Lamichhane, G. et al. Proc. Natl. Acad. Sci. USA 100, 7213–7218 (2003).
Graham, J.E. & Clark-Curtiss, J.E. Proc. Natl. Acad. Sci. USA 96, 11554–11559 (1999).
Faucher, S.P., Porwollik, S., Dozois, C.M., McClelland, M. & Daigle, F. Proc. Natl. Acad. Sci. USA 103, 1906–1911 (2006).
Boshoff, H.I. et al. J. Biol. Chem. 279, 40174–40184 (2004).
Andries, K. et al. Science 307, 223–227 (2005).
Matsumoto, M. et al. PLoS Med. 3, e466 (2006).
Author information
Authors and Affiliations
Ethics declarations
Competing interests
The authors declare no competing financial interests.
Rights and permissions
About this article
Cite this article
Lamichhane, G., Bishai, W. Defining the 'survivasome' of Mycobacterium tuberculosis. Nat Med 13, 280–282 (2007). https://doi.org/10.1038/nm0307-280
Issue Date:
DOI: https://doi.org/10.1038/nm0307-280
This article is cited by
-
The survival kit of Mycobacterium tuberculosis
Nature Medicine (2007)