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As our understanding of the mechanisms of cancer increases, so does our understanding of cancer therapies and responses to them. As part of our celebration for the 25th anniversary of Nature Medicine, we bring you a special focus on the most up-to-date approaches transforming the landscape of cancer therapy. Also check out the most recent clinical trials published in Nature Medicine and in Nature, as well as a selection of research in the emerging field of clinical genomics.
This collection combines published Research articles and Reviews from several Nature journals highlighting recent advances in our understanding of the role of the gut microbiota in health and disease, and the tools for studying these complex communities.
Human immunodeficiency virus (HIV) – the etiologic agent of AIDS – is one of the most intensively studied disease organism in history. Since its first identification in the early 1980s, HIV has transformed into a pandemic, globally infecting more 36 million people and annually contributing to the deaths of hundreds of thousands of patients – particularly in low income countries.
In health and biomedical applications, electronic technologies allow monitoring, sensing and extracting physiological data as well as correcting or supporting tissue function through electrical stimuli. This collection highlights the recent developments in materials science, electronics and biology of bioelectronic devices.
Stem cells are well on their way into the clinic and can be used in a variety of applications, such as disease modelling, drug screening and for regenerative medicine. This collection showcases research articles, reviews and protocols from across the Nature journals to highlight the striking advances made in basic and translational stem cell research.
In this collection, the cancer editorial community of the Nature journals presents the most recently published articles on cancer evolution. The topic is discussed from different angles (preclinical, translational and clinical), and across a range of tumour types.
Aging is associated with functional impairments in cellular pathways controlling genomic stability, proteostasis and metabolism, and is a major risk factor for several of the most prevalent diseases. This series of Reviews and Perspectives highlights the recent data that point toward the specific molecular pathways that are perturbed during aging and discuss potential ways to manipulate these pathways to prevent or alleviate age-related diseases.
There is an emerging understanding of how the disruption of immune homeostasis may lead to the development of chronic inflammatory diseases. This series of articles highlights new data that point toward the influence of environmental factors and addresses recent advances in our knowledge of the cell types and signaling pathways involved in inflammatory disease onset and progression.