Aims & Scope

The criteria for consideration of translational and clinical research in Nature Medicine are originality, timeliness and impact on improving human health by addressing unmet clinical needs. Original research ranges from new concepts in human biology and disease pathogenesis to new therapeutic modalities and drug development, to all phases of clinical work, as well as innovative technologies aimed at improving human health.

We consider all types of clinical research, including:

  • Case-reports and small case series
  • Clinical trials, whether phase 1, 2, 3 or 4
  • Observational studies
  • Meta-analyses
  • Biomarker studies   
  • Public and global health studies

Nature Medicine is also committed to facilitating communication between translational and clinical researchers. As such, we consider “hybrid” studies with preclinical and translational findings reported alongside data from clinical studies.

Clinical studies can be submitted in any of our content types. To facilitate the preparation of your clinical study, please review our guidelines and reporting requirements.

Current areas of interest also include, but are not limited to:

  • Gene and cell therapies
  • Clinical genomics
  • Regenerative medicine
  • High-definition medicine
  • Effects of the environment in human health
  • Artificial intelligence in health care
  • Smart wearable devices
  • Early disease diagnosis
  • Microbiome
  • Aging

Nature Medicine also publishes Reviews, Perspectives and other content commissioned from leading scientists in their fields to provide expert and contextualized views of the latest research driving the progress of medicine. The Magazine section is editorially independent and provides topical and timely reporting of upcoming trends affecting medicine, researchers and the general audience.